Physical activity habits are crucial for the physical and mental wellbeing of adolescents (individuals aged 10-19 years). However, few studies over the last two decades have systematically aggregated the influential factors of physical activity habits for adolescents. Five online databases (EBSCOhost (Eric), Psychology and Behavioral Sciences Collection, PubMed, Scopus, Web of Science) were searched for relevant studies published before 14 August 2022. Our systematic review indicated the following: 1) boys performed more physical activity habits than girls, whereas girls preferred to engage in moderate-to-vigorous physical activity; 2) physical activity in adolescents decreased with age; 3) African American adolescents performed significantly more habitual physical activities than white adolescents; 4) adolescents with higher literacy had better physical activity habits; 5) support from parents, teachers, friends, and others helped adolescents in developing physical activity habits; 6) adolescents who spent less time participating in habitual physical activity had a higher body mass index; 7) adolescents who reported higher levels of self-efficacy and satisfaction with school sports tended to have stronger physical activity habits; 8) sedentary behavior, smoking, drinking, prolonged screen time, negative emotions, and excessive use of media technology were correlated with reduced habitual physical activity in adolescents. These findings could help develop interventions to motivate adolescents and promote physical activity habits among them.
Overlapping disease aetiologies associated with multiple altered biological processes have been identified that change the endometrial function leading to recurrent implantation failure (RIF) and recurrent early pregnancy loss (REPL). We aimed to provide a detailed insight into the nature of the biological malfunction and related pathways of differentially expressed genes in RIF and REPL. Endometrial biopsies were obtained from 9 women experiencing RIF, REPL and control groups. Affymetrix microarray analysis was performed to measure the gene expression level of the endometrial biopsies. Unsupervised clustering of endometrial samples shows scattered distribution of gene expression between the RIF, REPL and control groups. 2556 and 1174 genes (p value < 0.05, Fold change > 1.2) were significantly altered in the endometria of RIF and REPL patients’ group, respectively compared to the control group. Downregulation in Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of the differentially expressed genes (DEGs) in RIF and REPL including ribosome and oxidative phosphorylation pathways. Gene Ontology (GO) analysis revealed ribosomes and mitochondria inner membrane as the most significantly downregulated cellular component (CC) affected in RIF and REPL. Determination of the dysregulated genes and related biological pathways in RIF and REPL will be key in understanding their molecular pathology and of major importance in addressing diagnosis, prognosis, and treatment issues