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  1. Nurhawa Mokhtar, Fatin Syuhadah Sulaiman, Anisa Kusumawardani, Taufiq Hidayat
    IIUM Medical Journal Malaysia, 2018;17(102):67-70.
    MyJurnal
    Breast milk contains all basic nutrition needed by a child. Exclusive breastfeeding is recommended to all infants in their first 6 months of life. Infants who had been exclusively breastfed have a better health status compared to infants who were introduced with mixed feeding in their early life. Exclusive breastfeeding not only gives benefits to the child, but also to the mother. In infants it offers protective mechanism in lowering risk of gastrointestinal infection and promotes bonding between the mother and the child. The first case was a 2 years and 7 months old girl who was admitted to Hospital Tengku Ampuan Afzan Kuantan due to acute gastroenteritis with some dehydration. She had been admitted a month earlier due to pneumonia. She was breast fed exclusively for 3 months after she was born. Formula feeding was started after she turned 4 months old.. The second case was a 1 year and 4 months old boy who was hospitalized due to acute bronchiolitis. He was not breast fed due to no milk production. Islam views childhood as a critical phase in molding an individual. Parents have been entrusted by Allah to observe and fulfill the rights of the children in providing a conducive environment for them to develop and grow. A good healthcare and proper nutrition are among the child’s rights that need to be filled by the parents. Islam emphasizes the importance of breastfeeding up to 2 years old as a way in providing good nutrition. Islam also provides solution for mothers who are unable to breastfed their child by adopting wet mother. Parents are responsible in providing good health and nutrition for their children. Breastfeeding is also highly encouraged by Islam because it provides medical benefits for both mother and children.
  2. Syafiqah Izzati Mahamad Fuad, Taufiq Hidayat, Fahisham Taib
    IIUM Medical Journal Malaysia, 2018;17(102):201-204.
    MyJurnal
    Childhood asthma is known to cause heavy economic burden due to increased hospital visits and prolonged hospital care due to its exacerbations. Despite the advancement of in-hospital management to control asthma, poor compliance has been an astounding problem in the management of the acute asthma attack. An8-year-old boy, who was known as persistent bronchial asthma since 5 year of age, have had frequent visits to the clinics and hospital due to poorly controlled asthma symptoms. During this episode, he presented with worsening shortness of breath. He often misses his daily medication due to parental assumption that the patient is able to manage asthma by himself. His non-compliance towards medications has led to patient’s absenteeism from school and deterioration in his academic performance. Islam is a religion that emphasizes on provision of individual’s and community’s health. This is achieved through taking an optimal care of one’s health and aimed at maintaining disease control state. Parents have the duty to provide their children with good and healthy living throughout the childhood period, and not to neglect them in any way.Islam stresses the importance not only self-care in the societybut also preservation of others’ health especially by the Muslim doctors. Conservation and protection of individual’s right to health especially children require group effort of both parents and medical personnel.
  3. Anisa Kusumawardani, Yunita Dewi Ardini, Taufiq Hidayat Hasan
    IIUM Medical Journal Malaysia, 2018;17(102):333-336.
    MyJurnal
    Dens evaginatus (DE) is a developmental anomaly. It is an extra cusp or tubercle that protrudes from the occlusal surface of posterior teeth, as well as the lingual surface of anterior teeth. Tubercles are susceptible to pulp exposure from wear or fracture because of malocclusion;leading to pulpal complications early after eruption.DE may also complicate the process of daily routine oral health care. A 13-year-old girl presented to our polyclinic with sinus track at the posterior lower left buccal gingiva forthe past1 year. All 35 teeth were sound. At the lingual side, there was an accessory tooth in close relation to tooth 35 covered with supra-gingival inflammation. Electric pulp test (EPT) showed that tooth 35 was already non-vital. Intra-oral periapical (IOPA) radiograph and cone beam computed tomography (CBCT) scan showed an abnormal-appearing root which shows DE with radiolucency at the periapical area. Root canal treatment was performed using crown down pressureless (CDP) technique and obturation was done using lateral condensation technique. The tooth was restored using composite restoration. DE is a rare condition. It is quite a challenge for dental practitioner since the diagnosis is difficult and the treatment options are limited. In the case of DE with necrotic pulp and periapical abscess, root canal treatment is a treatment of choice. We have to accept and appreciate any gift from Allah SWT whether it is good or bad, no equal divine creation except from Allah SWT.Therefore we need to take care of our oral hygiene to prevent diseases. In every disease, there is a cure; we thus need to try to do the best to find the cure and to not easily get rid of the tooth and replace it with a denture. Early diagnosis of DE can lead to proper treatment which can result in high success rate if it is followed by adequate restoration.
  4. Taufiq Hidayat, Zahoor Iqbal, Ariffin Nasir, Norsarwany Mohamad, Fahisham Taib
    MyJurnal
    Food is considered as a social responsibility of caregivers to their children. It has cultural connotation for all races notwithstanding their background and religious belief; that social responsibility should not be separated even in terminally ill patients. We recorded a case scenario of a terminally ill child who faced difficult end of life with inability to take oral fluids or food due to mechanical obstruction of duodenum by the pelvic rhabdomyosarcoma. From cultural context, the physical act of giving food and fluids to a sick person is considered “a display of one’s affection”. It is understandable that, once the dying phase has reached, and the body starts to shut down, administering fluids may not be useful despite it is deemed necessary from cultural point of view. This case illustrates an ethical dilemma in managing a child with end stage metastatic disease with multiple systemic complications, compounded with futility of medical care and complex social circumstances. It is quite challenging for physicians and relatives to provide good end of life care to patients in palliative care setting. Ensuring good quality of care, quality of life and quality of death are paramount to avoid suffering and distress among the patients and family members.
  5. Mossad AbdelHak Shaban Mohamed, Taufiq Hidayat, Asrar Abu Bakar, Azamin Anuar, Taher Halawa
    IIUM Medical Journal Malaysia, 2019;18(102):26-0.
    MyJurnal
    Productivity in medical field has inherent value in terms of improving our lives, which can expand our economies. Productivity in medicine has many aspects including improving clinical diagnostic skills, safety, and quality and quantity care. This study will assess whether early exposure to structured clinical reasoning coaching tools would improve their clinical decision making and productivity. Research question: Does clinical reasoning coaching tools Increase neonatal healthcare productivity? Materials and method: Medical practitioners recently joined neonatal units will participate over 2 years in an innovative series of clinical reasoning coaching sessions blended with virtual patients. Practitioners will be exposed to many teaching methods during the neonatal training that includes lectures, bedside teaching sessions and small group discussions beside website continuous contact for learning and chairing skills. Teaching series scope should cover resuscitating sick neonates, handling ventilators either conventional or high frequency, practicing common neonatal procedures, dealing with common neonatal scenarios, infection control policy and, effective communication skills The evaluation sessions will be introduced at the beginning of their training, during the course and at the end of the clerkship to assess their improving productivity, using diagnostic thinking inventory(DTI). Selection of the medical practitioners will be based on either on stratified random sampling or cohort control depending on the funding and logistic. All items will be analysed advanced statistical analysis methods. Results: The coaching tool may yield dramatic impact, allowing the innovators to be more productive. Suggesting widely utilize it for nurses, undergraduate and postgraduate medical Subspecialty. Conclusion: The research hypothesis is assuming that DTI scores and productivity will be higher after the coaching sessions as rated by the candidate’s performance.
  6. Muhamad Azamin Anuar, Asrar Abu Bakar, Mossad Abdelhak Shaban Mohamed, Taufiq Hidayat Hasan
    MyJurnal
    Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids is a rare inflammatory Central Nervous System disorder prominently affecting the brainstem. We present an adolescent’s reflection on this condition complicated with Epstein-Barr virus induced CNS Lymphoma. Case report: A 16-year-old boy presented about 5 years ago with a balance problem. He was diagnosed by MRI after ongoing debate whether this is juvenile multiple sclerosis. He initially responded to methylprednisolone but developed acute deterioration requiring 8 cycles of Infliximab and Methylprednisolone. He then confirmed cerebellar lymphoma 2 years later hence commenced on chemotherapy and radiotherapy after posterior fossa decompression. He gradually losses his motor skills, left hemiparesis and spasticity. He needs tracheostomy and gastrostomy due to poor bulbar function. Now, he is fully dependent and requires chest physiotherapy and suctioning and cystostomy for urinary incontinence. He has multiple PICU admissions due to recurrent aspiration, acute cerebellar oedema and post posterior fossa decompression. He worries about family breakdown as mum is his sole carer and having regular nightmare. He changed school to meet his care demands and unsure how to adapt to new environment. Social experience makes him anxious due to lack of understanding about his condition. He is evidently having low self-esteem and confidence. Discussion: Children palliative care team has been involved since diagnosis to support him and family. He is understandably depressed and clinical psychologist input bear minimal impact. He is fully aware of the current situation and his wish to rap Eminem’s songs like he used to do it before. Conclusion: Early aggressive treatment in CLIPPERS aim to prevent neuroaxonal loss. However, due to bellicose nature of the condition, the prognosis is relatively poor. Managing adolescent expectation after gradual deterioration is challenging especially, he is aware that achieving ‘normality’ is impossible as the treatment advancement still in limbo.
  7. Muhamad Azamin Anuar, Wan Alina Khadijah, Asrar Abu Bakar,, Mossad Abdelhak Shaban Mohamed, Taufiq Hidayat Hasan
    IIUM Medical Journal Malaysia, 2019;18(102):12-0.
    MyJurnal
    Acute onset quadriparesis can be a manifestation of a variety of neurological, metabolic or autoimmune conditions. Rarely, it could be one of many clinical presentations of juvenile dermatomyositis which belongs to the group of idiopathic inflammatory myopathies of childhood. We report the case of a 9-year old girl who presented with global myopathy over a two-month period. Case report: A 9-year-old girl referred with a 2 months history of generalised muscular pain and weakness. There were no significant history of preceded illness, trauma or excessive strenuous exercises. She had no other systemic complaints such as fever or skin rash. Past medical history was unremarkable except for recurrent tonsillitis. Physical examination revealed a child with normal alertness and behaviour. She has notable generalised swelling of all four limbs. Her neurological examination revealed normal tone however her power was definitely reduced in all four limbs (Graded 3/5). She demonstrated signs of proximal myopathy. Subsequent investigations revealed high Creatinine Kinase (CK) levels of 6470U/L, ESR 84mm/hr with deranged transaminases and positive serum mycoplasma and CMV IgM. Her MRI brain and spine along with lumbar puncture results were normal. She was referred to tertiary centre for further evaluation as her weakness progressed. An MRI muscle demonstrated marked inflammation in all four limbs including paravertebral muscles. Her muscle biopsy showed inflammatory myopathy leading to a diagnosis of juvenile dermatomyositis (JDM). She is now showing sustained clinical improvements following a course of immunoglobulin and corticosteroids therapy. Discussion: The diagnosis of JDM is generally considered in patients with rash-associated muscle weakness. Essentially, it involves assessment of muscle, skin, lung and cardiac involvement on top of baseline list of investigations that has been outline by Single Hub and Access point for pediatric Rheumatology in Europe (SHARE). This case reflects that JDM is possible despite non-existent of skin involvement.
  8. Mossad AbdelHak Shaban Mohamed, Taufiq Hidayat, Asrar Abu Bakar, Azamin Anuar, Mohd Fit'ri Akmal Mohd Sofee, Abdelbaset Taher Abdelhalim
    IIUM Medical Journal Malaysia, 2019;18(102):27-0.
    MyJurnal
    Neonates refers to the first 28 days of life, they are vulnerable to physiological changes. About 15% of neonates get admitted to NICU and a significant number of them end up in ventilation. This study assessed the beneficial role of non- pharmacological modalities on recovery with a better outcome of ventilated babies in NICU. Material and Methods: The study is a quantitative cross-sectional study for 9 months of NICU at IIUMMC. The study will include top conditions warranting neonatal intensive care unit (NICU) admissions and ventilation as preterm, respiratory distress, neonatal sepsis, HIE, and others. They are divided into two (2) groups; the first group will keep the standard practice and assigned as a control group. The second group will afford all or most of a package of non-pharmacological and sensory stimuli like a kangaroo, feeding, non-nutritive sucking, swaddling, skinto-skin contact, sensory saturation, soft massage, away irritant odour, Normal visual experience during daytime and dime light at night-time. decrease sound pollution, and voice stimulation assessing soft music or recitation of the Qur’an according to family preference. We will assess stabilizing vital signs, behavioural assessment, extubating timing, Short term outcome. Results: Adding non-pharmacological modalities could reduce the dose requirements for sedation and analgesics and has a positive effect on the neurodevelopmental outcome. Conclusion: nonpharmacological strategies besides other modalities improved short-term outcomes and the recovery of ventilated babies. The importance of coming back to nature, the effect of special senses and sensory stimulation on neonatal recovery, and ease extubation.
  9. Muhamad Azamin Anuar,, Mossad Abdelhak Shaban Mohamed, Nur Syuhada Mohd Azhar, Asrar Abu Bakar, Taufiq Hidayat Hasan
    IIUM Medical Journal Malaysia, 2019;18(102):13-0.
    MyJurnal
    Spinal tuberculosis in children is an established preventable disease in developing countries. Complications are devastating due to its aptitude to cause bone destruction, spinal deformity and paraplegia. Case report: We present an eight-month old girl with isolated gross motor regression and evolving spastic paraplegia. It highlights the challenge we encountered due to delay in garnering the pertinent investigation. She presented to clinic with history of legs weakness and loss of rolling after a period of prolonged febrile illness. Both parents are medical practitioners. Mother had history of SVT during pregnancy in spite on anti-arrhythmic treatments. Her father is a thalassaemia carrier. A thorough examination revealed gross motor delay and upper motor neuron signs. She had raised inflammatory markers, anaemia and thrombocytosis with persistent low-grade temperature. CT brain with contrast showed meningeal enhancement. Full septic work up revealed the CSF result reflecting partially treated meningitis. She was treated with third generation cephalosporin and acyclovir. Mother claimed exposure to TB patients hence Mantoux test was recommended which came positive. Her chest x-ray, sputum culture, CSF culture and NAA studies came non-conclusive for pulmonary tuberculosis. MRI for brain and spine showed features of tuberculous spondylodiscitis of T4-T5 vertebrae with associated subligamentous paravertebral spread and epidural extension causing spinal cord compression and T3-T6 hydro-syringomyelia. After multidisciplinary team discussion, patient started on intensive antituberculosis regimen with good initial response. Discussion: Clinically lower limbs power improved with good antigravity movement. Laboratory and radiological investigations have improved inflammatory markers and dropping trend thrombocytosis, and spinal gibbous stay stationary with improvement in plain radiology. She is under regular follow up awaiting serial MRI. Conclusion: The challenge in diagnosis of extra pulmonary tuberculosis in infants is getting them excluded early. High index of suspicion along with radiological investigation is vital to aid the diagnosis and establishment of treatment to expect a good outcome.
  10. Muhamad Azamin Anuar,, Asrar Abu Bakar, Sharifah Aishah Alsagoff, Amir Hamzah Abdul Rahman, Mossad Abdelhak Shaban Mohamed, Taufiq Hidayat Hasan
    IIUM Medical Journal Malaysia, 2019;18(102):15-0.
    MyJurnal
    In Malaysia, a course of vaccination DTaP/IPV/Hib was introduced in 2008, replacing the 2006 DwPT-HBV/Hib+OPV vaccines. Severe systemic adverse reactions after diphtheria, tetanus and pertussis vaccination are uncommon. Cardiac complications are rarely reported and is most probably implicated to the pertussis component. We describe a rare case of acute myocarditis that developed 60 hours after DTaP/IPV/Hib vaccination. Case report: A 2-month old infant presented to emergency department after her first diphtheria, tetanus and pertussis vaccination due to severe respiratory distress and cyanosis. She had her BCG and two Hepatitis B vaccinations previously with no major side effects. Parents reported that she was feverish for 48 hours post vaccination with no other associated symptoms. Prior to presentation, she went floppy and was immediately brought to hospital. On arrival, she was tachypnoeic and cyanotic with hypoperfusion and hypotensive. She was also noted to have hepatomegaly. She was grunting and her level of consciousness deteriorated. She was immediately intubated and her first blood gas showed profound metabolic acidosis with pH 6.6, base excess -24mmol/L, lactate 14mmol/L and bicarbonate 4mmol/L. She required fluid boluses and inotrope infusion was commenced. She received antibiotics and sodium bicarbonate to correct her acidosis. Her echocardiography showed global hypokinesia, CK 3018 and positive Troponin. She was treated with immunoglobulin for myocarditis and on high frequency oscillation for 4 days before being extubated on day 11 of admission. All her viral serology and cultures came back negative. Discussion: Cardiac complications after diphtheria, tetanus and pertussis and other vaccinations are exceptionally uncommon. This patient developed sudden onset cardiogenic deterioration after an expected fever-like illness post vaccination. Given her viral screening and cultures were negative, this make acute myocarditis post vaccination a remote possibility. We concur that evaluation of cardiac state should be considered in recently vaccinated infants who manifest with cyanosis, hypoperfusion and drowsiness.
  11. Muhamad Azamin Anua, Norlelawati A. Talib,, Nur Farah Izzati Misaridin, Asrar Abu Bakar, Mossad Abdelhak Mohamed, Taufiq Hidayat Hasan
    IIUM Medical Journal Malaysia, 2019;18(102):11-0.
    MyJurnal
    APDE is an acquired, transient bleeding disorder characterised by normal platelet counts with eosinophilia. It was previously known as ‘nonthrombocytopenic purpura with eosinophilia’. We report a case of a 3-year-old boy with prolonged history of spontaneous unexplained bruising which was initially investigated by SCAN team for non-accidental injury (NAI). Case report: A 3-yearold boy attended clinic with a 4-month history of recurrent bruising. Parents were unsure of preceded illness, but he remained well with no history of trauma. He has unremarkable medical history and father is a thalassaemia carrier. Upon assessment in clinic, he was subsequently referred for suspected NAI and SCAN team led to a police report with a plan to review in 2-months. Parents later decided to bring the child for further medical assessments which revealed multiple bruises over both thighs, back of shoulder, loin and trunk with varying sizes and ages. They were all non-tender on palpation with no recognisable shapes or patterns. Blood results showed normal liver functions with slightly prolonged APTT 39.8 secs. He has normal platelet count with significant eosinophilia 2.2 x 10^9/L and occasional reactive lymphocytes. Reflecting this result, plan for platelet functions and von Willebrand tests were made. However, due to costs, we decided to treat the child with antihelminthic agent for possible parasitic infestation. He had 3 days course of albendazole and no further bruises appeared after 5 days of completing treatment. Discussion: The clinical presentation of APDE can mimic Idiopathic Thrombocytopenic Purpura in many ways yet normal platelet counts often leads to a delay in diagnosis. Reassuringly, the course of APDE is benign and no treatment is often required. Conclusion: Investigations however are costly, therefore treatment with anti-helminthic agent would be an alternative option in providing assurance to family and medical practitioners dealing with suspected cases.
  12. Nur Zulfiqar Md A Azila, Siti Nursyahirah Mohd Tharmizi, Mohammad Nasser Hamed Mahmoud Bahbah, Taufiq Hidayat, Astrid K Kardani
    IIUM Medical Journal Malaysia, 2018;17(102):361-364.
    MyJurnal
    Acute glomerulonephritis is inflammation of the kidney mediated by an immunological process. Group A β-haemolytic streptococcal infection is common in children aged 5-12 years old and can lead to acute post-streptococcal glomerulonephritis which may develop after recovery from a streptococcal throat infection or skin infection (impetigo). 97% of cases occur in less developed country. The incidence has decreased in industrialized nations due to improved hygienic condition. A 7-year-old boy, the eldest child of 4 siblings from a divorced parent, was admitted to Hospital Tengku Ampuan Afzan Kuantan in March 2015 due to facial puffiness for 1 day duration. There was also dark colored urine. Patient had history of productive cough for 3 days and fever for 2 days. Father also complained of skin ulcer on patient’s right feet for about 1 month. There was hypertension (198/80 mmHg). Urine examination showed hematuria, proteinuria, and leucocyturia. Anti-streptolysin O titre was high (1:800) and complement C3 level was low (0.29). Patient was treated with antibiotic, diuretic, and anti-hypertension. The child is entrusted to the parents who will be called by the Almighty, who will ask them about this trust. Parents play vital role in maintaining and promoting the good health of the children. Parents should also pay attention to cleanliness, personal hygiene and the prevention of disease, especially infection. Islam paid attention to washing hands and cleansing the air inhaled into the lungs by regular cleaning of the nose as part of ablution before performing prayer. Parents are responsible in preserving life, health and growth of their children. Caring for cleanliness and hygiene is not only deemed a good habit in Islam but also rendered into rituals that constitute part of the faith itself.
  13. Zubi ZBH, Abdullah AFB, Helmi MABM, Hasan TH, Ramli N, Ali AABM, et al.
    Int J Pediatr, 2023;2023:3241607.
    PMID: 37705709 DOI: 10.1155/2023/3241607
    About 10% of newborns require some degree of assistance to begin their breathing, and 1% necessitates extensive resuscitation. Sick neonates are exposed to a number of invasive life-saving procedures as part of their management, either for investigation or for treatment. In order to support the neonates with the maximum possible benefits and reduce iatrogenic morbidity, health-care providers performing these procedures must be familiar with their indications, measurements, and potential complications. Hence, the aim of this review is to summarise ten of the main neonatal intensive care procedures with highlighting of their indications, measurements, and complications. They include the umbilical venous and arterial catheterizations and the intraosseous line which represent the principal postnatal emergency vascular accesses; the peripherally inserted central catheter for long-term venous access; the endotracheal tube and laryngeal mask airway for airway control and ventilation; chest tube for drainage of air and fluid from the thorax; and the nasogastric/orogastric tube for enteral feeding. Furthermore, lumber puncture and heel stick were included in this review as very important and frequently performed diagnostic procedures in the neonatal intensive care unit.
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