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  1. Yu YP, Raveendran P, Lim CL
    Biomed Opt Express, 2015 Jul 1;6(7):2466-80.
    PMID: 26203374 DOI: 10.1364/BOE.6.002466
    This paper shows how dynamic heart rate measurements that are typically obtained from sensors mounted near to the heart can also be obtained from video sequences. In this study, two experiments are carried out where a video camera captures the facial images of the seven subjects. The first experiment involves the measurement of subjects' increasing heart rates (79 to 150 beats per minute (BPM)) while cycling whereas the second involves falling heart beats (153 to 88 BPM). In this study, independent component analysis (ICA) is combined with mutual information to ensure accuracy is not compromised in the use of short video duration. While both experiments are going on measures of heartbeat using the Polar heart rate monitor is also taken to compare with the findings of the proposed method. Overall experimental results show the proposed method can be used to measure dynamic heart rates where the root mean square error (RMSE) and the correlation coefficient are 1.88 BPM and 0.99 respectively.
  2. Yu YP, Raveendran P, Lim CL, Kwan BH
    Biomed Opt Express, 2015 Nov 1;6(11):4610-8.
    PMID: 26601022 DOI: 10.1364/BOE.6.004610
    In this paper, facial images from various video sequences are used to obtain a heart rate reading. In this study, a video camera is used to capture the facial images of eight subjects whose heart rates vary dynamically, between 81 and 153 BPM. Principal component analysis (PCA) is used to recover the blood volume pulses (BVP) which can be used for the heart rate estimation. An important consideration for accuracy of the dynamic heart rate estimation is to determine the shortest video duration that realizes it. This video duration is chosen when the six principal components (PC) are least correlated amongst them. When this is achieved, the first PC is used to obtain the heart rate. The results obtained from the proposed method are compared to the readings obtained from the Polar heart rate monitor. Experimental results show the proposed method is able to estimate the dynamic heart rate readings using less computational requirements when compared to the existing method. The mean absolute error and the standard deviation of the absolute errors between experimental readings and actual readings are 2.18 BPM and 1.71 BPM respectively.
  3. Lim PK, Ng SC, Lovell NH, Yu YP, Tan MP, McCombie D, et al.
    Physiol Meas, 2018 10 11;39(10):105005.
    PMID: 30183675 DOI: 10.1088/1361-6579/aadf1e
    OBJECTIVE: The photoplethysmography (PPG) signal, commonly used in the healthcare settings, is easily affected by movement artefact leading to errors in the extracted heart rate and SpO2 estimates. This study aims to develop an online artefact detection system based on adaptive (dynamic) template matching, suitable for continuous PPG monitoring during daily living activities or in the intensive care units (ICUs).

    APPROACH: Several master templates are initially generated by applying principal component analysis to data obtained from the PhysioNet MIMIC II database. The master template is then updated with each incoming clean PPG pulse. The correlation coefficient is used to classify the PPG pulse into either good or bad quality categories. The performance of our algorithm was evaluated using data obtained from two different sources: (i) our own data collected from 19 healthy subjects using the wearable Sotera Visi Mobile system (Sotera Wireless Inc.) as they performed various movement types; and (ii) ICU data provided by the PhysioNet MIMIC II database. The developed algorithm was evaluated against a manually annotated 'gold standard' (GS).

    MAIN RESULTS: Our algorithm achieved an overall accuracy of 91.5%  ±  2.9%, with a sensitivity of 94.1%  ±  2.7% and a specificity of 89.7%  ±  5.1%, when tested on our own data. When applying the algorithm to data from the PhysioNet MIMIC II database, it achieved an accuracy of 98.0%, with a sensitivity and specificity of 99.0% and 96.1%, respectively.

    SIGNIFICANCE: The proposed method is simple and robust against individual variations in the PPG characteristics, thus making it suitable for a diverse range of datasets. Integration of the proposed artefact detection technique into remote monitoring devices could enhance reliability of the PPG-derived physiological parameters.

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