Forest clearing for agriculture plantations and local community settlements may trigger food insecurity, which causes poor development, predominantly in Orang Asli children. This cross-sectional study was conducted to determine the relationships between food security and anthropometric and cognitive function among Orang Asli children in Temerloh, Pahang. Materials and methods:A total of one hundred and sixty-seven children (ages 7 to 11) from five selected Orang Asli villages (Kampung Sungai Enggang, Kampung Penderas, Kampung Pasu, Kampung Lubok Wong, and Kampung Pian) were involved in this study. The food security index was assessed using the Radimer/Cornell Hunger and Food Insecurity Instrument. Anthropometric indices were based on height-for-age and BMI-for-age Z-scores, while cognitive performance was tested using Raven’s Coloured Progressive Matrices (R-CPM). Results:A majority (91.6%) of the respondents reported some kind of food insecurity (12.6% household food insecure, 74.2% individual food insecure, and 4.8% child hunger). Rates of stunting, thinness, and overweight/obesity were 25.8%, 16.2%, and 18.0%, respectively. A majority (46.1%) of the children had average cognitive scores, followed by below average (38.3%) and above average (15.6%), respectively. Height-for-age was significantly associated with cognitive function (p=0.008). Among sociodemographic factors, household size (p=0.007) and household income (p
High lipid levels are associated with the increase tendency of atherosclerosis formation. In the pathogenesis of atherosclerosis, increase in low density lipoprotein cholesterol (LDL-c) concentration has been identified as the main culprit in many cardiovascular disease (CVD) incidents. Both quercetin and kaempferol are flavonoids that most abundantly found in fruits and vegetables. Several studies have dictated that both compounds exhibit CVD protective effects through the regulation of lipid levels. In the present study, the hypolipidemic potential of quercetin and kaempferol through LDL-c uptake were tested on HepG2 cells. Cell viability was determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay in order to study the cytotoxicity effect quercetin and kaemperol on cell proliferation. The present study demonstrated that quercetin and kaempferol at low concentration of 15 µM, possess the highest hypolipidemic effects via LDL-c uptake in HepG2 cells (p