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  1. Hisham AN, Azlina AF, Aina EN, Sarojah A
    Eur J Surg, 2001 Jun;167(6):403-5.
    PMID: 11471662 DOI: 10.1080/110241501750243725
    OBJECTIVE: To review our experience of total thyroidectomy for bilateral multinodular goitre.
    DESIGN: Prospective open study.
    SETTING: Teaching hospital, Malaysia.
    SUBJECTS: 98 consecutive patients whose bilateral multinodular goitres were treated by total thyroidectomy, January 1998-November 1999.
    INTERVENTION: A revised technique of total thyroidectomy in which more attention than is customary was paid to the exposure and safety of the laryngeal nerves and the parathyroid glands. All patients had at least 1 parathyroid gland autotransplanted.
    MAIN OUTCOME MEASURES: Morbidity and mortality
    RESULTS: There were no injuries to the recurrent laryngeal nerves and no patient developed persistent hypocalcaemia; 27/98 developed transient hypocalcaemia, but this had settled by 6 months postoperatively. 59 patients had persistent symptoms of pressure preoperatively, and these all resolved by 3 months postoperatively. 6 patients had occult malignant disease discovered on histological examination, and 3 developed minor wound infections.
    CONCLUSIONS: Total thyroidectomy is the procedure of choice for bilateral multinodular goitres, provided that sufficient attention is paid to the preservation of the laryngeal nerves and the parathyroid glands.
  2. Aina EN, Hisham AN
    Eur J Surg, 2001 Sep;167(9):662-5.
    PMID: 11759734 DOI: 10.1080/11024150152619282
    OBJECTIVE: To find out the incidence and type of external laryngeal nerves during operations on the thyroid, and to assess the role of a nerve stimulator in detecting them.
    DESIGN: Prospective, non-randomised study.
    SETTING: Teaching hospital, Malaysia.
    SUBJECTS: 317 patients who had 447 dissections between early January 1998 and late November 1999.
    MAIN OUTCOME MEASURES:
    Number and type of nerves crossing the cricothyroid space, and the usefulness of the nerve stimulator in finding them.
    RESULTS: The nerve stimulator was used in 206/447 dissections (46%). 392 external laryngeal nerves were seen (88%), of which 196/206 (95%) were detected with the stimulator. However, without the stimulator 196 nerves were detected out of 241 dissections (81%). The stimulator detected 47 (23%) Type I nerves (nerve > 1 cm from the upper edge of superior pole); 86 (42%) Type IIa nerves (nerve < 1 cm from the upper edge of superior pole); and 63 (31%) Type IIb nerves (nerve below upper edge of superior pole). 10 nerves were not detected. When the stimulator was not used the corresponding figures were 32 (13%), 113 (47%), and 51 (21%), and 45 nerves were not seen. If the nerve cannot be found we recommend dissection of capsule close to the medial border of the upper pole of the thyroid to avoid injury to the nerve.
    CONCLUSION: Although the use of the nerve stimulator seems desirable, it confers no added advantage in finding the nerve. In the event of uncertainty about whether a structure is the nerve, the stimulator may help to confirm it. However, exposure of the cricothyroid space is most important for good exposure in searching for the external laryngeal nerve.
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