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  1. Fulltext Safe delivery of two parturient women in severe metabolic acidosis
    Shariffuddin II, Rai V, Chan YK, Muniandy RK
    BMJ Case Rep, 2014;2014.
    PMID: 24862427 DOI: 10.1136/bcr-2014-205135
    Care of an acutely ill parturient is particularly difficult when we have to balance the needs of both mother and the fetus to survive. The literature suggests there should be emphasis on stabilising the mother's condition. In dealing with metabolic acidosis, however, we believe delivering the baby early might not only relieve the threat of the acidosis on the mother, it may be the only way to deliver a live baby. We report two parturient women with severe metabolic acidosis which was considerably reduced very soon after the delivery and how our timely delivery resulted in the birth of two neurologically intact babies.
    Matched MeSH terms: Cholecystitis, Acute/etiology
  2. Fulltext The impact of routine histopathological examination on cholecystectomy specimens from an Asian demographic
    Chin KF, Mohammad AA, Khoo YY, Krishnasamy T
    Ann R Coll Surg Engl, 2012 Apr;94(3):165-9.
    PMID: 22507719 DOI: 10.1308/003588412X13171221501708
    INTRODUCTION: Most gallbladder carcinoma cases are suspected pre-operatively or intra-operatively. In Malaysia histopathological examination of cholecystectomy specimens has become routine practice. The aim of this study was to assess the impact of routine histological examinations on cholecystectomy specimens from an Asian demographic, which may differ from a Caucasian demographic.

    METHODS: A retrospective study was performed of all histopathology reports for cholecystectomies (laparoscopic and open) undertaken over a period of 12 years (1997-2008) in a single teaching hospital.

    RESULTS: A total of 1,375 gallbladder specimens were sent for histopathological analysis, with 7 (0.5%) being reported as malignant while only three (0.2%) were found to contain primary gallbladder carcinoma. Other premalignant findings included two specimens with dysplastic changes of the mucosa and one tubulovillous adenoma with a dysplastic epithelium. From the ten malignant and premalignant specimens, seven were diagnosed pre-operatively, two were suspected intra-operatively and one was diagnosed with dysplastic changes on the histopathology report post-operatively.

    CONCLUSIONS: This study supports earlier research carried out in the UK and the demographic difference does not affect the impact of the histology examination on cholecystectomy specimens in diagnosing this disease. A selective policy is recommended in Malaysia.

    Matched MeSH terms: Cholecystitis, Acute/etiology
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