Displaying all 9 publications

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  1. Goh CF, Ming LC, Wong LC
    Clin Dermatol, 2021;39(2):314-322.
    PMID: 34272029 DOI: 10.1016/j.clindermatol.2020.09.005
    Infection preventive practice of using disinfectants against SARS-CoV-2 has become the new normal due to the COVID-19 pandemic. Although disinfectants may not be applied directly to the human body, it remains at high risk of exposure including close skin contact on disinfected surfaces or during handling. This dermal contact, on a regular basis, can induce hazardous skin reactions like irritation, inflammation, and burning in severe conditions. Disinfectants are germicide chemicals that can penetrate the skin and create skin reactions that are usually regarded as irritant and allergic contact dermatitis. More importantly, disinfectants can react with skin components (proteins and lipids) to facilitate their skin penetration and disrupt the skin barrier function. Whereas the antimicrobial actions of disinfectants are well understood, much less is known regarding their dermatologic reactions, including but not limited to irritation and hypersensitivity. We reviewed the skin reactions created by those disinfectants against SARS-CoV-2 approved by the European Chemical Agency and the US Environmental Protection Agency.
    Matched MeSH terms: Dermatitis, Allergic Contact/etiology*
  2. Mohamed KB
    Contact Derm., 1998 Apr;38(4):224-5.
    PMID: 9565305
    Matched MeSH terms: Dermatitis, Allergic Contact/etiology*
  3. How KN, Tang MM, Kaur R, Johar A
    Med J Malaysia, 2017 04;72(2):113-118.
    PMID: 28473674 MyJurnal
    BACKGROUND: The pattern of contact sensitisation should be monitored in order to detect the changing trend of sensitising allergens. We aim to evaluate contact sensitisation in adults suspected to have allergic contact dermatitis.

    METHODS: This is a five-year retrospective review on contact sensitisation in adults patch-tested with the European Standard and extended series between 2011 and 2015 in the Department of Dermatology, Hospital Kuala Lumpur.

    RESULTS: There were 689 adults (M:F= 1:2.04; mean age 40.5 years) who were patch-tested. The majority (175, 25.4%) were white collar workers and 118 (17.1%) were healthcare workers. The provisional diagnoses of patients included contact dermatitis (80.8%); endogenous eczema (7.9%); hand eczema (3.2%); hand and foot eczema (3.5%); foot eczema (1.4%) and photodermatitis (1.2%). The allergens selected for testing were based on past and present history of exposure. Almost all (688, 99.8%) were patch-tested with the European standard allergens and 466 (67.6%) were tested with the extended series. About three quarter (528, 76.6%) developed at least one positive reaction. The top five most frequent reactions were to nickel sulphate (35.3%); potassium dichromate (16.5%); methylchloroisothiazolinone (12.9%), fragrance mix I (12.6%), and cobalt chloride (10.2%). The commonest sensitisations identified in the extended series were palladium chloride (23/105, 21.9%), stannous chloride (18/85, 21.2%), miconazole (7/44, 15.9%), gold(I)sodium thiosulfate (16/105, 15.2%) and thimerosal (29/202, 14.4%).

    CONCLUSION: Contact sensitisation was detected in 76.6% of adults patch-tested. Nickel sulphate was found to be the most frequently sensitising allergen. The rising prevalence of methylchloroisothiazolinone/methylisothiazolinone sensitization poses significant concern.

    Matched MeSH terms: Dermatitis, Allergic Contact/etiology
  4. Chaubal TV, Bapat RA, Bapat PR
    Contact Derm., 2017 Nov;77(5):325-326.
    PMID: 29063688 DOI: 10.1111/cod.12819
    Matched MeSH terms: Dermatitis, Allergic Contact/etiology
  5. Chaubal TV, Bapat RA, Shetty D
    Contact Derm., 2017 Oct;77(4):251-252.
    PMID: 28872204 DOI: 10.1111/cod.12794
    Matched MeSH terms: Dermatitis, Allergic Contact/etiology
  6. Shah V, Chaubal TV, Bapat RA, Shetty D
    Contact Derm., 2017 Dec;77(6):407-408.
    PMID: 29164691 DOI: 10.1111/cod.12779
    Matched MeSH terms: Dermatitis, Allergic Contact/etiology
  7. Chaubal TV, Bapat RA, Patil PG, Shetty A
    Contact Derm., 2016 Oct;75(4):256-7.
    PMID: 27620128 DOI: 10.1111/cod.12625
    Matched MeSH terms: Dermatitis, Allergic Contact/etiology*
  8. Yap FBB
    Dermatitis, 2010 May-Jun;21(3):179-81.
    PMID: 20487668
    Matched MeSH terms: Dermatitis, Allergic Contact/etiology*
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