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  1. Ishak MF, Aminuddin BS, Asma A, Lokman BS, Ruszymah BH, Goh BS
    Med J Malaysia, 2008 Jul;63 Suppl A:117-8.
    PMID: 19025013
    Chondrocytes were isolated from normal and microtic human auricular cartilage after ear surgery carried out at Universiti Kebangsaan Malaysia Medical Centre. Chondrocytes were cultured and expanded until passage 4. After reached confluence, cultured chondrocytes at each passage (P1, P2, P3 and P4) were harvested and assigned for growth profile analysis. There was no significant difference in cell viability between both normal and microtic samples (p = 0.84). Both samples showed no significant differences for growth profile parameters in terms of growth rate, population doubling time and total number of cell doubling, except in passage 1, where there is significant difference in cell growth rate (p = 0.004). This preliminary data has indicated that chondrocytes from microtic cartilage has the potential to be used in the reconstruction of human pinna in the future.
    Matched MeSH terms: Ear Cartilage/cytology*
  2. Ishak MF, See GB, Hui CK, Abdullah Ab, Saim Lb, Saim Ab, et al.
    Int J Pediatr Otorhinolaryngol, 2015 Oct;79(10):1634-9.
    PMID: 26250439 DOI: 10.1016/j.ijporl.2015.06.034
    This study aimed to isolate, culture-expand and characterize the chondrocytes isolated from microtic cartilage and evaluate its potential as a cell source for ear cartilage reconstruction. Specific attention was to construct the auricular cartilage tissue by using fibrin as scaffold.
    Matched MeSH terms: Ear Cartilage/cytology*
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