Displaying all 3 publications

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  1. Zulkifli A
    Med J Malaysia, 1979 Jun;33(4):360-1.
    PMID: 522751
    Matched MeSH terms: Factor VII Deficiency/complications*
  2. Abdullah WZ, Ismail R, Nasir A, Mohamad N, Hassan R
    Fetal Pediatr Pathol, 2013 Apr;32(2):77-81.
    PMID: 22536947 DOI: 10.3109/15513815.2012.671447
    Combined factor V and VIII deficiency is a rare bleeding disorder. Diagnosis of congenital coagulation factor deficiency in a neonate is challenging due to "immaturity" of the hemostatic system. A 2-day-old baby girl presented with spontaneous cephalhematoma. She was found to have persistent abnormal coagulation tests and finally diagnosed as combined factor V and VIII deficiency. Interestingly, factor V and factor VIII in developmental hemostasis are quite similar with adult levels in newborn, and hence early diagnosis is possible. An investigation to detect underlying hemostatic defects is recommended in newborns with spontaneous cephalhematoma.
    Matched MeSH terms: Factor VII Deficiency/complications*
  3. Fadzil F
    Med J Malaysia, 2011 Aug;66(3):261-3.
    PMID: 22111455
    Inherited factor VII (FVII) deficiency is a rare autosomal recessive hemorrhagic disorder. Clinical bleeding can vary widely and does not always correlate with the level of FVII coagulant activity measured in plasma. Most severe cases of factor VII (FVII) deficiency are diagnosed during childhood, often during the first 6 months of life. In infancy, the most common sites of bleeding occur in the gastrointestinal tract or CNS, accounting for 60-70% of bleeds in this age group. Recombinant factor VIIa (rFVIIa) is one such agent, which has been shown to prevent hematoma expansion and improve outcome in acute intracranial haemorrhages. The purpose of this case report is to share our experience regarding the usefulness of rFVIIa in the management of acute intracranial haemorrhage.
    Matched MeSH terms: Factor VII Deficiency/complications*
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