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  1. Lam J, El Nsouli D, Lee EL, Alqeisi T, Kane R, McGonagle I, et al.
    BMJ Open, 2024 Dec 23;14(12):e093636.
    PMID: 39719285 DOI: 10.1136/bmjopen-2024-093636
    OBJECTIVES: We sought to review studies that examine healthcare professionals' and students' knowledge, attitudes and practices (KAP) regarding medication disposal. We also explore recommendations and barriers related to appropriate medication disposal.

    DESIGN: A systematic review was conducted that adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses.

    DATA SOURCES: MEDLINE, Embase, CINAHL, Web of Science, PsycINFO and Google Scholar were searched up to 23 February 2024.

    STUDY ELIGIBILITY CRITERIA AND SETTING: Qualitative, quantitative and mixed-method primary research studies. There was no limitation on the publication date, geographical locations or the study settings.

    PARTICIPANTS: Pharmacists, doctors, nurses and students from these respective professional groups in any country.

    PRIMARY OUTCOME MEASURES: The levels of healthcare staff and students' KAPs about disposal of unwanted medications.

    DATE EXTRACTION AND SYNTHESIS: Data extraction was conducted by four of the researchers independently. The study details were categorised into three main domains, that is, KAP using the KAP model. Other relevant information was also extracted, and synthesised in overall themes, such as challenges and recommendations.

    RESULTS: Thirty-seven studies from 18 countries (Asia n=21, the USA n=7, Africa n=5, EU n=2, South America n=2) were included. 86.5% (n=32) investigated participants' knowledge of medication disposal. Although there was a good level of awareness about the environmental impacts, there were significant gaps in knowledge regarding correct disposal methods, available services, guidelines and training. Thirty studies explored participants' attitudes towards medication disposal. There was a generally positive attitude towards the need for environmentally safe disposal practices. Thirty-five studies evaluated participants' practices in relation to medication disposal. Although there was generally a positive attitude and some understanding of appropriate disposal methods, the majority of the participants did not follow the practice guidelines, especially outside healthcare settings.

    DISCUSSIONS AND CONCLUSIONS: Although healthcare staff and students have fair knowledge and positive attitudes towards medicine disposal, their actual practices are lacking. One significant challenge identified is the limited awareness about proper disposal methods coupled with a lack of established services or guidelines. Even in cases where take-back programmes are available, they often face issues with accessibility. To tackle these challenges, it is suggested that governmental bodies should establish and enforce clear policies on medication disposal while also expanding educational initiatives to increase understanding among professionals and students. Furthermore, improving access to take-back programmes is crucial for ensuring safe medication disposal and minimising potential environmental and health hazards.

    PROSPERO REGISTRATION NUMBER: CRD42024503162.

    Matched MeSH terms: Medical Waste Disposal/standards
  2. Sapkota B, Pariatamby A
    Waste Manag, 2025 Mar;195:107-128.
    PMID: 39908624 DOI: 10.1016/j.wasman.2025.01.039
    Although healthcare waste management (HCWM) legislations prevail in Association of Southeast Asian Nations (ASEAN), there appears a prominent gap in standalone pharmaceutical waste management (PWM) legislation making harmonization of PWM challenging in the region. This review is aimed to comprehensively overview the PWM-related legislations in ASEAN, comprising of 10 economically rising countries in Southeast Asia. The relevant regulatory documents, that were promulgated till August 31, 2024 and that were in English or officially translated in English, were extracted from PubMed/Medline, Scopus, Science Direct, Google Scholar, and respective country's government websites. The documents were considered suitable based on their relevance, accessibility, and timeliness. The policy analysis revealed that all Member States in ASEAN lack specific legislations on PWM, and are managing pharmaceutical waste (PW) within the umbrella legislation of HCWM or biomedical waste management. The review discussed implications of joint ASEAN legislations, relevant guiding principles of waste management, and international guidelines relevant to PWM such as Basel Convention, Stockholm Convention, and the status of their endorsement in ASEAN. Some ASEAN countries such as Indonesia, Malaysia, Philippines, Singapore, Thailand and Vietnam have established infrastructures and regulatory setup for HCWM but still lack specific PWM legislations. ASEAN can foster harmonized legislative frameworks, facilities and technologies in PWM, raising public awareness and active participation to mitigate PW problem. The hard laws such as Acts, regulations, and ordinances are definitely aimed for PWM in ASEAN, but at least harmonized soft laws in the form of guidelines are imperative to harmonize PWM practice.
    Matched MeSH terms: Medical Waste Disposal/standards
  3. Ishak AS, Haque MS, Sadhra SS
    Occup Med (Lond), 2019 Apr 13;69(2):99-105.
    PMID: 30295884 DOI: 10.1093/occmed/kqy129
    BACKGROUND: Needlestick injury (NSI) is a significant occupational health issue among healthcare workers (HCWs).

    AIMS: To determine the national self-reported incidence and risk factors for NSI among Malaysian Ministry of Health (MOH) HCWs.

    METHODS: Using data from the MOH national sharps injury surveillance programme, information on reported NSIs over a 1-year period (2016) for different HCW subgroups were extracted and analysed.

    RESULTS: A total of 1234 NSI cases were reported in 2016, giving an overall incidence of 6 injuries per 1000 HCWs. Medical doctors recorded the highest incidence (21.1 per 1000 HCWs) followed by dental staff (7.5), pharmacy staff (4.2), nurses (3.7), medical assistants (3.4) and allied and auxiliary staff (1.0). Doctors had significantly increased risk of NSI compared with allied and auxiliary staff (relative risk [RR] = 20.7, 95% confidence interval [CI] 15.5-27.5), medical assistants (RR = 6.1, 95% CI 4.5-8.2), nurses (RR = 5.7, 95% CI 5.0-6.6), pharmacy staff (RR = 5.0, 95% CI 3.7-6.6) and dental staff (RR = 2.8, 95% CI 2.2-3.5). Significant differences were found in age and sharps- handling experience between occupational subgroups (P < 0.001 for both variables). Male employees had higher risk than females (RR = 1.33, 95% CI 1.18-1.50), with a significant difference seen in their sharps-handling experience (P < 0.01). Important risk factors included unsafe practices such as recapping of needles and their improper disposal.

    CONCLUSIONS: The national incidence of NSI amongst Malaysian HCWs was lower compared with other countries, but unsafe practices remain an important concern. There is a need to formulate, implement and monitor safe and consistent practices for the different healthcare professionals.

    Matched MeSH terms: Medical Waste Disposal/standards
  4. Amir Sultan MM, Goh CT, Wan Puteh SE, Mokhtar M
    Int J Health Care Qual Assur, 2019 Feb 11;32(1):34-44.
    PMID: 30859864 DOI: 10.1108/IJHCQA-08-2017-0161
    PURPOSE: Mercury is widely used in medical and healthcare facilities as dental amalgam, mercury-added medical devices, thiomersal-containing vaccines, laboratory analysis and for other general applications despite the hazards. Various agencies consistently promote mercury-free medical facilities through mercury-free alternatives and better management practices, which are in line with the Minamata Convention on Mercury that aims to protect human health and environment from anthropogenic mercury release. The paper aims to discuss these issues.

    DESIGN/METHODOLOGY/APPROACH: The authors conducted a gap analysis on recommended practices gathered from the literature and current practices gathered through semi-structured interviews with Malaysian medical personnel. A life cycle approach was adopted covering mercury use: input, storage, handling, accident, waste disposal and governance phases.

    FINDINGS: The authors found that there are significant gaps between recommended and current mercury management practices. Analysis indicates improper mercury management as the main contributor to these gaps. The authors found from recommended practices that core components needing improvement include: mercury management action plan, mercury use identification team, purchasing policy, proper guidelines and monitoring systems.

    PRACTICAL IMPLICATIONS: This study helps us to understand mercury management practices and suggests essential steps to establish a mercury-free medical facility.

    ORIGINALITY/VALUE: This study explored the gaps between recommended and current mercury management practices in a medical facility and contributes to the Minamata Convention on Mercury aspirations.

    Matched MeSH terms: Medical Waste Disposal/standards*
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