MyMedR

Chronic ectopic pregnancy--a challenge in diagnosis

Menon R

Med J Malaysia, 1973 Dec;28(2):88-90.

PMID: 4276222

Matched MeSH terms: Pregnancy, Ectopic/etiology

Fulltext Peritoneal trophoblastic implant

Rachagan SP, Kutty K, Govindan KS

Med J Malaysia, 1997 Sep;52(3):293-4.

PMID: 10968101

A case of persistent trophoblastic tissue on the pelvic peritoneum is presented. While most cases are secondary to conservative surgery for tubal ectopic pregnancy, primary implantation can also occur as highlighted by this case. A brief pathophysiology of the condition is presented. The importance of monitoring the serum for beta subunit human chorionic gonadotrophin (HCG) is emphasised.

Matched MeSH terms: Pregnancy, Ectopic/etiology*

Ectopic pregnancy--a study of 77 cases

Lim MA

Med J Malaysia, 1974 Mar;28(3):171-5.

PMID: 4278064

Matched MeSH terms: Pregnancy, Ectopic/etiology

Fulltext Cesarean scar pregnancy: What can we offer?

Ng BK, Lim PS, Ahmad S, Kampan NC, Abdul Karim AK, Omar MH

Taiwan J Obstet Gynecol, 2015 Apr;54(2):208-10.

PMID: 25951734 DOI: 10.1016/j.tjog.2014.11.022

Matched MeSH terms: Pregnancy, Ectopic/etiology

Fulltext Evaluation of treatment of previous cesarean scar pregnancy with methotrexate: a systematic review and meta-analysis

Salari N, Kazeminia M, Shohaimi S, Nankali AA, Mohammadi M

Reprod Biol Endocrinol, 2020 Nov 09;18(1):108.

PMID: 33168010 DOI: 10.1186/s12958-020-00666-0

BACKGROUND: Previous caesarean scar pregnancy is one type of ectopic pregnancy in myometrium and fibrous tissue of previous caesarean scar. One of the therapeutic methods of this type of ectopic pregnancy is treatment with methotrexate. Given various findings on the treatment of caesarean scar pregnancy with methotrexate and lack of global report in this regard, we aimed to achieve a global report on the treatment of CSP with methotrexate through related literature review and analysis of the results of the studies, to enable more precise planning to reduce complications of CSP.

METHOD: This review study extracted information through searching national and international databases of SID،, Embase, ScienceDirect, ، Scopus, ، PubMed, Web of Science (ISI) between 2003 and January 2020. To perform the meta-analysis, random-effects model and heterogeneity of the studies with I2 index were investigated. Data were sanalysed using Comprehensive Meta-Analysis version 2.

RESULTS: In total, 26 articles with a sample size of 600 individuals were enrolled in the meta-analysis. According to the results of the study, the mean level of β-hCG was 28,744.98 ± 4425.1 mIU/ml before the intervention and was 23,836.78 ± 4533.1 mIU/ml after the intervention. The mean intraoperative blood loss (ml) was 4.8 ± 3.76 ml, mean hospital stay (days) was 11.7 ± 1.2 days, mean time for serum-hCG normalization (days) was 41.6 ± 3.2 days, success was 90.7% (95% CI: 86.7-93.5%), and complication was 9% (95% CI: 6.3-12.8%).

CONCLUSION: The results of the current study show methotrexate significantly reduces β-hCG levels and can be effective in treating caesarean scar pregnancy and its complications.

Matched MeSH terms: Pregnancy, Ectopic/etiology

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