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Fulltext Determination of trimester specific reference intervals for thyroid hormones during pregnancy in Malaysian women

Thevarajah M, Chew YY, Lim SC, Sabir N, Sickan J

Malays J Pathol, 2009 Jun;31(1):23-7.

PMID: 19694310 MyJurnal

To establish trimester specific reference intervals for thyroid hormones during pregnancy in Malaysian women.

Matched MeSH terms: Pregnancy Trimesters/blood*

Increase in maternal adiposity and poor lipid profile is associated with oxidative stress markers during pregnancy

Loy SL, KNS S, JM HJ

Prev Med, 2013;57 Suppl:S41-4.

PMID: 23219759 DOI: 10.1016/j.ypmed.2012.11.021

This study aimed to evaluate changes in maternal adiposity and lipid profile and to correlate these parameters with Deoxyribonucleic acid (DNA) damage and total antioxidant capacity (TAC) levels among pregnant women.

Matched MeSH terms: Pregnancy Trimesters/blood

Associations between prenatal nicotine exposure, oxidative stress, and postpartum visceral fat

Loy SL, Jan Mohamed HJ

Women Health, 2014;54(2):145-60.

PMID: 24329183 DOI: 10.1080/03630242.2013.870632

This study aimed to examine the associations among prenatal nicotine exposure, oxidative stress, and postpartum visceral fat among women exposed to secondhand smoke (SHS). The study was conducted in Kelantan, Malaysia, from April 2010 to December 2012. Blood samples were collected in the second and third trimesters from 135 healthy pregnant women who were followed-up at delivery, 2 months, 6 months and 12 months postpartum. Maternal hair nicotine and oxidative stress markers during pregnancy were measured. Visceral fat was assessed by bioelectrical impedance. Multiple linear regression analysis revealed that maternal hair nicotine concentration was associated with increased DNA damage (tail moment: β=0.580, p=0.001) and decreased glutathione peroxidase (β=-12.100; p=0.009) in the second trimester of pregnancy. Increased DNA damage, protein oxidation and total antioxidant capacity in the second trimester were associated with 2, 6, and 12 months postpartum visceral fat. No direct association was found between prenatal hair nicotine level and postpartum visceral fat; however, these results suggest that any relation of SHS to visceral adiposity may be indirect, mediated via enhanced oxidative stress.

Matched MeSH terms: Pregnancy Trimesters/blood

Fulltext Risk factors for antenatal hypovitaminosis D in an urban district in Malaysia

Bukhary NBI, Isa ZM, Shamsuddin K, Lin KG, Mahdy ZA, Hassan H, et al.

BMC Pregnancy Childbirth, 2016 07 13;16(1):156.

PMID: 27411716 DOI: 10.1186/s12884-016-0939-3

BACKGROUND: Pregnant women form one of the high risk groups facing hypovitaminosis D. Low level of vitamin D will affect directly or indirectly both mother and fetus. Screening vitamin D in the first trimester of pregnancy is important to determine the necessary preventive action. Therefore, this study was aimed to determine the prevalence of hypovitaminosis D and its risk factors among pregnant women in the first trimester.

METHODS: A cross sectional study was carried out among first trimester pregnant women during their first antenatal visit. Samples were taken from different ethnicities in an urban district in Malaysia. A total of 396 respondents (99 % response rate) aged 18-40 years completed self-administered and guided questionnaire (characteristics and risk factors), validated semi-quantitative food frequency questionnaire for vitamin D in Malaysia (FFQ vitamin D/My), anthropometric measures (weight and height), blood test for serum 25(OH)D, skin measurement using Mexameter (MX 18) and Fitzpatrick Skin Type Chart Measurement (FSTCM). Data were analyzed to determine the association between risk factors and hypovitaminosis D.

RESULTS: The prevalence of hypovitaminosis D (serum 25(OH)D

Matched MeSH terms: Pregnancy Trimesters/blood*

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