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  1. Kow CS, Ramachandram DS, Hasan SS
    Int Immunopharmacol, 2022 Feb;103:108455.
    PMID: 34959188 DOI: 10.1016/j.intimp.2021.108455
    Matched MeSH terms: Pyrazines/therapeutic use*
  2. Li G, Sng KS, Shu B, Wang YJ, Yao M, Cui XJ
    Eur J Pharmacol, 2023 Apr 15;945:175524.
    PMID: 36803629 DOI: 10.1016/j.ejphar.2023.175524
    Spinal cord injury (SCI) is a serious disabling condition that leads to the loss of motor, sensory, and excretory functions, seriously affecting the quality of life of patients and imposing a heavy burden on the patient's family and society. There is currently a lack of effective treatments for SCI. However, a large number of experimental studies have shown beneficial effects of tetramethylpyrazine (TMP). We performed a meta-analysis to systematically evaluate the effects of TMP on neurological and motor function recovery in rats with acute SCI. English (PubMed, Web of Science, and EMbase) and Chinese (CNKI, Wanfang, VIP, and CBM) databases were searched for literature related to TMP treatment in rats with SCI published until October 2022. Two researchers independently read the included studies, extracted the data, and evaluated their quality. A total of 29 studies were included, and a risk of bias assessment revealed that the methodological quality of the included studies was low. The results of the meta-analysis showed that the Basso, Beattie, and Bresnahan (BBB; n = 429, pooled mean difference [MD] = 3.44, 95% confidence interval [CI] = 2.67 to 4.22, p 
    Matched MeSH terms: Pyrazines/therapeutic use
  3. Aravind SR, Ismail SB, Balamurugan R, Gupta JB, Wadhwa T, Loh SM, et al.
    Curr Med Res Opin, 2012 Aug;28(8):1289-96.
    PMID: 22738801 DOI: 10.1185/03007995.2012.707119
    To compare the incidence of symptomatic hypoglycemia between sitagliptin and sulfonylurea in Muslim patients with type 2 diabetes who fasted during Ramadan.
    Matched MeSH terms: Pyrazines/therapeutic use
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