Salvadora percisa (popularly known as miswak) has been widely used as an aid for
oral hygiene in dentate patient. There is no side effect of using miswak stick. A new approach
introduced the role of miswak stick in edentulous patient. It may prevent the incidence of denture
stomatitis among denture wearer. This study assessed the effectiveness of the miswak stick as an
oral aid in edentulous patients as an alternative treatment for denture stomatitis. (Copied from article).
The objective of this study is to determine the therapeutic efficacy of allicin against Candida albicans (C. albicans) and Staphylococcus aureus (S. aureus), the common etiological agents for denture stomatitis (DS). The minimum inhibitory concentration (MICs), minimum bactericidal concentrations (MBCs) and minimum fungicidal concentration (MFCs) of allicin were determined by the broth microdilution method followed by checkerboard microdilution method for a synergistic interaction between allicin + nystatin and allicin + CHX. The potential of allicin to eradicate C. albicans and S. aureus biofilms was assessed by treating biofilm formed on self- polymerized acrylic resin with allicin at a sub-MIC concentration for 5 min. The commercial denture cleanser (brand X) was used as a positive control. A Kruskal-Wallis test followed by the post-hoc Mann-Whitney U test was applied (SPSS 20.0), and the level of significance was set at P