Browse publications by year: 1972

  1. Chandrasekharan N
    Aust N Z J Surg, 1972 Feb;38(3):292-297.
    PMID: 29265290 DOI: 10.1111/j.1445-2197.1972.tb05640.x
    This paper reports a study in the rat of the changes in the plasma albumin level following laparotomy, and their correlation with the concentrations of extravascular albumin in the area of the operation wound and in the liver.

    SUMMARY: The pathogenesis of postoperative hypoalbuminaemia remains a controversial and poorly understood topic. In the present study the changes in the plasma albumin level following laparotomy have been investigated by immunological methods and correlated with the concentrations of extravascular albumin in the operation wound site and in the liver. There was a fall in the plasma albumin level, accompanied by an increase in the extravascular albumin concentration at the laparotomy wound site, with no alteration in the concentration of albumin in the liver. This work confirms that postoperative hypoalbuminaemia is due to accumulation of albumin in the wound site. Increased capillary permeability is suggested as a cause of the excessive loss of plasma albumin into the surgically injured site. The role and subsequent fate of the extravascular albumin in the wound area are also discussed.

  2. Balasegaram M
    Ann. Surg., 1972 Feb;175(2):149-54..
    PMID: 5059599
    MeSH terms: Biliary Tract Diseases/complications; Calculi/complications*; Calculi/etiology*; Calculi/surgery*; Cholangiography; Hepatectomy; Humans; Liver Diseases/complications*; Liver Diseases/etiology*; Liver Diseases/surgery*; Male; Middle Aged
  3. Balasegaram M
    Ann. Surg., 1972 Apr;175(4):528-34.
    PMID: 4259839
    MeSH terms: Adolescent; Adult; Aged; Angiography; Child; Child, Preschool; Debridement; Diagnosis, Differential; Drainage; Clinical Enzyme Tests; Female; Humans; Liver/surgery; Liver Abscess, Amebic/diagnosis*; Liver Abscess, Amebic/surgery*; Liver Regeneration; Male; Middle Aged; Laparoscopy; Portography; Radionuclide Imaging; Suppuration/microbiology; Vena Cava, Inferior
  4. Prasad U, Rajamani R
    Singapore Med J, 1972 Oct;13(5):239-44.
    PMID: 4651729
    Papillomas of nose and paranasal sinuses are uncommon tumours. Based on the detailed clinical and
    histopathological examination of seven cases of papillomas, the authors would accept and recommend
    t~e. su~ested unifying name of transitional cell papilloma for these lesions which may further be sub·
    dIvIded onto Type I and Type II. The rationale behind this classification is discussed at length. There is
    a greater tendency for Type II papillomas to recur and undergo malignant change. It is suggested that
    Type I papillomas be managed by relatively simple surgical procedures whereas Type II cases be dealt with more radically.
    MeSH terms: Adult; Female; Hospitals, University; Humans; Malaysia; Male; Middle Aged; Nose Neoplasms; Papilloma*
  5. Loh TG, Chawla JC
    Singapore Med J, 1972 Dec;13(6):298-304.
    PMID: 4657200
    Complicated migraine is not well known. It is associated with transient and protean sensory and motor
    nenrological features although disturbance of mood, affect and psyche has also been described.
    This paper is based on a study of ten patients suffering from complicated migraine and attempt is made
    to describe various neurological symptoms and signs.
    It becomes apparent from this study that there arc diverse manifestations of this interesting disorder.
    Furthermore complicated migraine seems to affect a younger age group and there may not be any
    family history of migraine. In most cases the nenrological symptoms precede the attacks of headaches.
    The nenrological deficit may persist after longer periods. Initially, the attacks arc usnally followed by
    complete recovery, with repeated attacks there may be residual neurological deficit. Though the exact
    aetiology of the migraine remains unknown, it has been suggested that it is due to spasm or oedema of
    cerebral vascular system. If the vessels involved are the carotid artery system, the symptoms and signs
    obviously would be due to involvement of cerebral hemisphere, whereas affection of basilar artery
    would produce signs and symptoms of cerebellar or brain stem deficiency.
    At times it may be extremely difficult to differentiate between a typical attack of migraine and headache
    due to an underlying pathology e.g. intracranial angioma or space occupying lesions, which may
    require investigations such as angiography. The angiography may prove fruitless and cause deterioration
    in neurological signs. A careful follow-up should be planned for cases with complicated migraine
    to exclude any underlying pathology.
    MeSH terms: Adolescent; Adult; Case Reports*; China/ethnology; Female; Hospitals, University; Humans; Malaysia; Malaysia/ethnology; Male; Migraine Disorders*
  6. Steinberg AG, Eng LI
    Hum. Hered., 1972;22(3):254-8.
    PMID: 4116753
    MeSH terms: gamma-Globulins/analysis; Gene Frequency; Genetic Code; Genetics, Population*; Humans; Immunoglobulin G/analysis*; Immunoglobulin Fragments; Immunoglobulin Fc Fragments*; Malaysia; Phenotype; Protein Conformation; African Continental Ancestry Group; Asian Continental Ancestry Group
  7. Miller AB, Nunn AJ, Robinson DK, Fox W, Somasundaram PR, Tall R
    Bull. World Health Organ., 1972;47(2):211-27.
    PMID: 4118761
    As part of a large-scale international cooperative investigation into the side effects of thioacetazone-containing regimens in the treatment of tuberculosis, an evaluation has been made of the variation in the frequency of side effects between different countries and between different centres in the same country and of the likely reasons for this variation. In 3 countries patients of different racial origin were under observation in the same hospital. Over a 12-week period of treatment there was considerable variation between the countries and centres in the overall frequency of side effects and of those leading to a major departure from prescribed treatment, the variation being similar for the two thioacetazone-containing regimens and for the streptomycin plus isoniazid control regimen, though at a lower level for the latter. In Malaysia, Singapore, and Trinidad, where different racial groups were under treatment, there was no clear indication that race was an important factor in explaining the differences between countries, except for cutaneous side effects in Trinidad and possibly in Malaysia.It is concluded that the differences in the frequency of side effects to thioacetazone-containing regimens probably result from variation in the closeness of supervision of patients, in the recording and interpretation of side effects, and in environmental factors including the previous use of other medicaments or exposure to sensitizing substances.
    MeSH terms: Adult; Africa, Northern; Antitubercular Agents/adverse effects*; Asia; Czechoslovakia; Drug Hypersensitivity*; Female; Geography; Humans; International Cooperation; Male; Middle Aged; Thioacetazone/adverse effects*; Trinidad and Tobago; Tuberculosis, Pulmonary/drug therapy*; Continental Population Groups
  8. Arumanayagam P, San SF
    Int J Epidemiol, 1972;1(2):101-9.
    PMID: 4204766 DOI: 10.1093/ije/1.2.101
    Three countries which were under British influence, Ceylon, Malaysia and Singapore developed their health services earlier to suit the plantation industry in Ceylon, the plantation and mining industries in Malaysia and the mainly urban population of Singapore. With the attainment of independent status the governments paid more attention to providing total health care, preventive and curative, with special attention being paid to the development of health services in rural areas. Demographic trends, pattern of diseases and other health indicators of the countries are outlined. The health trends seen also reflect the socio-economic development in these countries. The pressures of a rapidly growing population both in Ceylon and Malaysia are complicating the health problems.
    MeSH terms: Birth Rate; Cardiovascular Diseases/mortality; Health Expenditures; Female; Fertility; Health*; Humans; Infant Mortality; Infant, Newborn; Life Expectancy; Malaria/epidemiology; Malaysia; Male; Maternal Mortality; Mortality; Neoplasms/mortality; Parasitic Diseases/mortality; Parasitic Diseases/epidemiology; Poliomyelitis/epidemiology; Population Growth; Pregnancy; Singapore; Smallpox/epidemiology; Sri Lanka
  9. Kendall MN
    Int Nurs Rev, 1972;19(3):246-60.
    PMID: 4484348
    MeSH terms: Education, Nursing, Diploma Programs*; Great Britain; Indian Ocean Islands; International Educational Exchange*; Jamaica; Malaysia; Statistics as Topic; West Indies
  10. Dunn FL
    Bull. World Health Organ., 1972;46(1):99-113.
    PMID: 4537337
    Surveys were conducted in the southern Malay peninsula to assess intestinal parasitism in the aboriginal ethnic minority groups. Faecal specimens from 1 273 persons were examined by the thiomersal-iodine-formol direct-smear technique. Prevalences are reported and, for helminth infections, data on worm burdens. The state of sanitation in each of 9 cultural-ecological groups was assessed by means of a simplified system of scoring for variables. Particular attention was paid to relationships between cultural and ecological factors, sanitation, and observed patterns of intestinal parasitism. The author also discusses the fact that the number of parasitic species diminishes in habitats simplified by man, whereas an increase occurs in the prevalence and intensity of the more adaptable species that persist in ecosystems of low complexity.
    MeSH terms: Adolescent; Adult; Child; Child, Preschool; Environmental Health; Ethnic Groups; Female; Humans; Infant; Infant, Newborn; Intestinal Diseases, Parasitic/epidemiology*; Malaysia; Male; Parasite Egg Count; Asian Continental Ancestry Group
  11. Macdonald WW, Rajapaksa N
    Bull. World Health Organ., 1972;46(2):203-9.
    PMID: 4537482
    Although dengue haemorrhagic fever is widely established in South-East Asia, no cases have been reported from Borneo. In order to help to assess whether the infection could become established in Borneo, a survey was made, using the single-larva collection method, of the distribution and prevalence of the principal vector, Aedes aegypti, in Sabah and in a few towns and villages of Brunei and Sarawak. In addition, the prevalence of Ae. aegypti was compared with that of certain other species of Aedes.Ae. aegypti was found to be well established in the north, east, and south-west of Sabah but to be absent from almost all of the west coast. It was either uncommon in, or absent from, several small coastal villages; in others, very high Breteau indices were recorded. No reasonable explanation for this discontinuous distribution can be suggested. Large numbers of potential larval habitats were found, giving reason to believe that Ae. aegypti will spread further within these territories.
    MeSH terms: Aedes*; Animals; Borneo; Larva; Malaysia; Population Density
  12. Lam SK
    Bull. World Health Organ., 1972;47(1):127-9.
    PMID: 4538899
    Rubella antibody rates in the female population of Kuala Lumpur were lower than those reported from temperate countries, though similar to rates found in other tropical countries excepting Singapore. Among the major ethnic groups, the immunity status of the Chinese was higher than that of the Malay and Indian groups.
    MeSH terms: Adolescent; Adult; Antibodies/analysis*; Child; Child, Preschool; Ethnic Groups; Female; Hemagglutination Inhibition Tests; Humans; Infant; Malaysia; Rubella/immunology*
  13. Cadigan FC, Andre RG, Bolton M, Gan E, Walker JS
    PMID: 4561007
    MeSH terms: Adolescent; Adult; Child; Child, Preschool; Ecology; Fluorescent Antibody Technique; Humans; Infant; Malaysia; Plants; Scrub Typhus/diagnosis; Scrub Typhus/epidemiology*; Serologic Tests
  14. Andre RG, Cadigan FC, Fredericks HJ, Fong YL
    Trans. R. Soc. Trop. Med. Hyg., 1972;66(4):644-52.
    PMID: 4561008
    MeSH terms: Chloroquine/administration & dosage; Chloroquine/blood; Chloroquine/therapeutic use*; Drug Resistance, Microbial*; Humans; Malaria/drug therapy*; Malaria/epidemiology; Malaysia; Microbial Sensitivity Tests; Plasmodium falciparum/drug effects*; Plasmodium falciparum/isolation & purification
  15. Welch QB, Lie-Injo Luan Eng, Bolton JM
    Hum. Hered., 1972;22(1):28-37.
    PMID: 4624781
    MeSH terms: Alleles; Blood Protein Electrophoresis; Carbonic Anhydrases/blood*; Electrophoresis, Starch Gel; Gene Frequency; Genetics, Population; Hemoglobins/analysis; Hemoglobins, Abnormal/analysis; Heterozygote; Humans; Malaysia; Phenotype; Phosphoglucomutase/blood*; Asian Continental Ancestry Group
  16. Lie-Injo LE, Fix A, Bolton JM, Gilman RH
    Acta Haematol., 1972;47(4):210-6.
    PMID: 4625303
    MeSH terms: Adult; Electrophoresis; Electrophoresis, Paper; Elliptocytosis, Hereditary*; Ethnic Groups; Female; Gels; Genes; Hemoglobins, Abnormal*; Humans; Malaysia; Male; Pedigree; Population Surveillance; Starch
  17. Eng LI, Welch QB
    Hum. Hered., 1972;22(4):338-43.
    PMID: 4647199
    MeSH terms: Adult; Electrophoresis, Starch Gel; Female; Gene Frequency; Genetics, Population*; Glucose-6-Phosphate Isomerase/blood*; Humans; Infant, Newborn; Isoenzymes/blood; Malaysia; Male; Phenotype; Phosphogluconate Dehydrogenase/blood*; Continental Population Groups
  18. Simons RC, Sarbadhikary D
    Int J Soc Psychiatry, 1972;18(2):97-103.
    PMID: 4650925
    MeSH terms: Adult; Age Factors; Mental Disorders/complications; Educational Status; Ethnic Groups; Family Characteristics; Female; Humans; Malaysia; Male; Occupations; Religion; Sex Factors; Social Behavior Disorders/complications
  19. Welch QB, Lie-Injo LE
    Hum. Hered., 1972;22(5):503-7.
    PMID: 4670071
    MeSH terms: Blood Protein Electrophoresis; Electrophoresis, Disc; Genetics, Population; Humans; Hydrogen-Ion Concentration; Malaysia; Phenotype; Serum Albumin*; Genetic Variation*; European Continental Ancestry Group; Asian Continental Ancestry Group
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