Browse publications by year: 1978

  1. Rajakumar MK
    Family Practitioner, 1978;3:7-8.
    MeSH terms: Hypertension
  2. Klein H, Jäger HJ, Domes W, Wong CH
    Oecologia, 1978 Jan;33(2):203-208.
    PMID: 28309164 DOI: 10.1007/BF00344848
    SO2-fumigation experiments were conducted with plants of pea (Pisum sativum) and corn (Zea mays) recognized to be, respectively, sensitive and tolerant to the gas. Accumulation of inorganic sulfur in the tissues revealed that the pea takes up considerably greater amounts of SO2 than corn. Porometer measurements and transpiration coefficients show that this greater SO2 uptake is partly related to the lower leaf diffusion resistance of peas. Additional internal sinks for SO2 uptake are discussed in order to give a complete explanation of the differential SO2 uptake of the two species.
  3. Hasma H, Subramaniam A
    Lipids, 1978 Dec;13(12):905-7.
    PMID: 27520427 DOI: 10.1007/BF02533847
    Methyl esters from the triglyceride fraction of the neutral lipids of natural rubber latex were found by gas liquid chromatography to contain about 90% of a furanoid acid. Spectroscopic analysis identified the acid as 10,13-epoxy-11-methyloctadeca-10,12-dienoic acid.
  4. Thomas V, Dissanaike AS
    PMID: 97821
    Sera from 243 donors belonging to the four main ethnic groups in West Malaysia (Orang Asli, Malays, Chinese and Indians) were tested, using the indirect fluorescent antibody technique for the prevalence of antibodies to Sarcocystis. Almost 20% reacted positively at dilutions of 1:64 or higher and eight among the Orang Asli and Malays gave the highest titres of 1:256. Prevalence was highest in the Orang Asli and lowest in Chinese. 22 sera also reacted positively to Toxoplasma, whether due to polyparasitism or cross-reaction is, as yet, unknown.
    MeSH terms: Antibodies/analysis; Humans; Malaysia; Sarcocystis/immunology*; Toxoplasma/immunology; Continental Population Groups
  5. Lie-Injo LE, Ganesan J, Herrera A, Lopez CG
    Hum. Hered., 1978;28(1):37-40.
    PMID: 304028
    In a study of Malaysians of different racial groups, 1,510 sera (908 from Malays, 371 from Chinese and 231 from Indians) were identified for their protease inhibitor (Pi) types. The gene frequencies for the alleles PiM, PiS and PiX in Malays were, respectively, 0.979, 0.015, and 0.007. In Chinese, the frequencies were 0.981, 0.019 and 0.000, and in Indians they were 0.976, 0.24, and 0.000. It is interesting that the usually rare PiX type is found in appreciable frequency in the Malays. Two different types with unusual behavior and obscure origin were also found.
    MeSH terms: Alleles; alpha 1-Antitrypsin/genetics*; China/ethnology; Humans; India/ethnology; Malaysia; Phenotype; Genetic Variation*
  6. Chan KL, Dhaliwal SS, Yong HS
    Comp. Biochem. Physiol., B, 1978;59(4):345-51.
    PMID: 318285
    1. Electrophoretic variations of 9 erythrocyte proteins, coded by a separate gene locus each, were analysed in and among the 5 Malayan species of Rattus belonging to the subgenus Lenothrix. 2. The average proportion of loci heterozygous per individual for the taxa analysed is 0.037. 3. The results obtained confirm the specific status of the 5 taxa studied. With respect to the relative affinities among the species studied, the present results could resolve the discrepancies between conclusions based on morphological evidence and those based on cytological evidence. 4. The 5 species of Rattus studied may be assigned to 4 groups and comparative data suggest that these groups are relatively distantly related to one another.
    MeSH terms: Animals; Blood Proteins/genetics; Blood Proteins/isolation & purification*; Muridae/blood*; Rodentia/blood; Species Specificity; Genetic Variation; Rats
  7. Iyngkaran N, Lee IL, Robinson MJ
    Scand. J. Infect. Dis., 1978;10(3):243-6.
    PMID: 362519
    A new metronidazole derivative, Tiberal (Ro-07-0207, Roche Laboratories), was evaluated in 22 children with Giardia lamblia infection. Seven patients received an oral dose of 1 g twice daily for one day; the remaining 15 patients received a single dose of 50 mg/kg. Parasitological cure was noted in all 22 patients. Significant side effects were observed only in those children who received the drug at the higher dosage regime. The present study also confirms the findings of other authors that a mucosal imprint method is more reliable than examination of stools, duodenal juice or jejunal biopsy material for the detection of G. lamblia infection.
    MeSH terms: Administration, Oral; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Duodenum/parasitology; Feces/parasitology; Female; Giardiasis/drug therapy*; Humans; Infant; Intestinal Mucosa/parasitology; Intestinal Secretions/parasitology; Jejunum/parasitology; Malaysia; Male; Nitroimidazoles/therapeutic use*; Ornidazole/administration & dosage; Ornidazole/therapeutic use*
  8. Brown GW, Robinson DM, Huxsoll DL
    Am. J. Trop. Med. Hyg., 1978 Jan;27(1 Pt 1):121-3.
    PMID: 415625
    Two communities of Orang Asli (aborigines) in Peninsular Malaysia were observed for evidence of Rickettsia tsutsugamushi infection over periods of 1-8 mo. Sequential sera were examined for antibody by the indirect immunofluorescence test. The incidence of infection in the two self-selected populations in the two communities was calculated to be 3.9% per month and 3.2% per month.
    MeSH terms: Adolescent; Adult; Antibodies, Bacterial/analysis*; Child; Child, Preschool; Fluorescent Antibody Technique; Humans; Infant; Malaysia; Middle Aged; Orientia tsutsugamushi/immunology; Scrub Typhus/epidemiology*
  9. Kuntz RE
    Am. J. Trop. Med. Hyg., 1978 Jan;27(1 Pt 1):208-9.
    PMID: 415627
    Eleven pairs of schistosomes, indistinguishable from the classical Schistosoma japonicum, were found in a monkey (Macaca fascicularis) taken near Ranau in North Borneo. The new locality is within the recorded range of the species which extends from Japan, China, Taiwan, and Philippines through Southeast Asia to the Celebes.
    MeSH terms: Animals; Haplorhini; Borneo; Macaca fascicularis; Monkey Diseases*; Schistosomiasis/veterinary*
  10. Welch QB, Shu LC, Thangavelu S, Lie-Injo EL
    Hum. Hered., 1978;28(1):62-5.
    PMID: 618819
    812 West Malaysian Orang Asli belonging to four ethnic groups were surveyed for adenosine deaminase (ADA; EC using starch gel electrophoresis. Only the common ADA1 and ADA2 alleles were found, with the frequencies of the latter being 0.025, 0.103, 0.115 and 0.028 in the Semai, Semelai, Temuan, and Jakun groups, respectively. A new 'breeding genetic distance' was applied to these gene frequencies and the Semelai and Temuan were found to be more closely related to each other, and to have considerably more evolutionary flexibility on this scale of 'micro-evolution' than the other two groups. The Semai and Jakun were more similar to each other on the basis of these ADA gene frequencies.
    MeSH terms: Adenosine Deaminase/genetics*; Consanguinity; Humans; Malaysia; Nucleoside Deaminases/genetics*; Phenotype; Polymorphism, Genetic*; Genetic Variation
  11. Fix AG
    Ann. Hum. Genet., 1978 Jan;41(3):329-39.
    PMID: 626477
    Most current models of human population structure view migration solely as a deterministic force reducing the variance in gene frequencies among the local colonies of a subdivided population. By an empirical example and through simulation experiments, it is shown that migration structured along kinship lines (by analogy to the lineal or 'kinship' effect) does not always reduce the variances of gene frequencies arising through intergenerational random genetic drift. Thus populations experiencing high rates of migration may not be genetically homogenous.
    MeSH terms: Ethnic Groups; Gene Frequency; Gene Pool; Genetics, Population*; Humans; Malaysia; Models, Biological; Genetic Variation*
  12. Murugasu R, Wang F, Dissanaike AS
    Trans. R. Soc. Trop. Med. Hyg., 1978;72(4):389-91.
    PMID: 705845
    The first living patient with a Schistosoma japonicum-type infection who presented with the nephrotic syndrome is reported in detail. It is not clear whether the nephrotic syndrome was due to the schistosome infection or to the deposition of hepatitis B antigen and antibody complexes. This is the tenth case of schistosomiasis reported from aborigines in Malaysia and a sylvatic source of infection is suggested.
    MeSH terms: Adult; Hepatitis B/complications; Humans; Liver/parasitology; Malaysia; Male; Nephrotic Syndrome/etiology; Schistosoma japonicum
  13. Kan SK, Kay RW
    PMID: 725999
    Previous reports of melioidosis in Sabah are reviewed and a detailed account of a case, presenting as prostatitis, in a 40-year-old British male is given. The history suggested that the organism, Pseudomonas pseudomallei, was transmitted by a fly which entered the eye. Diagnosis was delayed and treatment presented some difficulty, the organism being relatively insensitive to amplicillin and gentamicin. Co-trimoxazole was the most effective, followed by minocycline. Cure was eventually achieved and after four years the patient was fit and normal, except for sterility.
    MeSH terms: Adult; Ampicillin/therapeutic use; Drug Combinations; Gentamicins/therapeutic use; Humans; Infertility, Male/etiology; Malaysia; Male; Melioidosis/complications; Melioidosis/diagnosis*; Melioidosis/drug therapy; Minocycline/therapeutic use; Prostatitis/etiology*; Sulfamethoxazole/therapeutic use; Trimethoprim/therapeutic use
  14. Simons MJ, Chan SH, Wee GB, Shanmugaratnam K, Goh EH, Ho JH, et al.
    PMID: 730194
    New data are presented concerning the relationship between NPC and HLA antigens among Chinese. When attention is confined to newly diagnosed cases, it can be shown that, apart from the increased risk associated with the joint occurrence of A2 and B-Sin 2, there is also an increased risk associated with BW17 and a decrease in risk associated with A11. Among long-term survivors, however, BW17 is appreciably decreased, whereas A2 in the absence of B-Sin 2 or BW17 is increased. Among Malays, a non-Chinese group, there is an excess among NPC patients of a locus A blank, a blank which is probably associated with the AW19 complex.
    MeSH terms: Carcinoma/etiology; Carcinoma/genetics; Carcinoma/immunology*; Carcinoma/mortality; China; Chromosome Mapping; Gene Frequency; Genes; HLA Antigens/analysis*; HLA Antigens/genetics; Humans; Malaysia; Nasopharyngeal Neoplasms/etiology; Nasopharyngeal Neoplasms/genetics; Nasopharyngeal Neoplasms/immunology*; Nasopharyngeal Neoplasms/mortality; Phenotype
  15. Williamson NE
    Popul Bull, 1978 Jan;33(1):1-35.
    PMID: 12260443
    MeSH terms: Africa; Argentina; Asia; Asia, Southeastern; Asia, Western; Bangladesh; Behavior; Birth Rate; Chile; China; Demography; Economics; Europe; Europe, Eastern; Far East; Hong Kong; Hungary; India; Israel; Japan; Korea; Latin America; Malaysia; Mortality; Nigeria; North America; Nuclear Family; Psychology; Research*; Sex*; Sex Preselection; Social Values; Socioeconomic Factors*; South America; Taiwan; Time Factors; United States
  16. Pryor RJ
    J Trop Geogr, 1978;46:61-75.
    PMID: 12262749
    MeSH terms: Asia; Asia, Southeastern; Demography; Developing Countries; Emigration and Immigration; Malaysia; Population; Population Dynamics*
  17. Sidhu MS
    J Trop Geogr, 1978;46:76-85.
    PMID: 12262750
    MeSH terms: Asia; Asia, Southeastern; Culture; Demography*; Developing Countries; Ethnic Groups*; Geography; Malaysia; Population; Population Characteristics*
  18. Narayanan S
    Malay Econ Rev, 1978;23(2):53-60.
    PMID: 12262802
    MeSH terms: Asia; Asia, Southeastern; Demography; Developing Countries; Emigration and Immigration; Malaysia; Population; Population Dynamics*
  19. PMID: 12277967
    MeSH terms: Asia; Asia, Southeastern; Behavior; Community Health Workers*; Developing Countries; Economics*; Education; Family Planning Services; Goals*; Health Planning*; Malaysia; Mass Media; Motivation*; Organization and Administration; Population Control*; Psychology; Public Policy; Rural Population; Sex Education*; Socioeconomic Factors; Women's Rights*
  20. Soon L
    J Dev Areas, 1978;13(1):35-48.
    PMID: 12310729
    MeSH terms: Asia; Asia, Southeastern; Demography; Developing Countries; Emigration and Immigration; Malaysia; Population; Population Dynamics*
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