Browse publications by year: 1981

  1. Lie-Injo LE, Herrera AR, Kan YW
    Nucleic Acids Res., 1981 Aug 11;9(15):3707-17.
    PMID: 6269090
    DNA from healthy Malaysian newborns was studied on gene maps after digestion with different restriction endonucleases. Of 65 newborns, two were found to be carriers of two different variants of triplicated alpha-globin loci. In variant no. 1, found in an Malay, the three alpha-globin genes are in an elongated DNA fragment on digestion with Eco RI and Bam HI. The third alpha-globin gene was found in a additional 3.7-kb fragment on digestion with Hpa I, Bgl II and Hind III. In variant no. 2, a new type of triplicated alpha-globin loci, found in a Chinese, the three alpha-globin genes reside in an elongated DNA fragment longer than that of variant no. 1 on digestion with Eco RI and Bam HI. The third alpha-globin gene was found in an additional 4.2-kb fragment on digestion with Hpa I and Hind III. Digestion of this variant DNA with Bg1 II produced an abnormal 16.7-kb fragment in addition to the normal 7.0-kb Bgl-II fragment. The locations of the restriction sites in the two types of triplicated alpha-globin loci are compatible with a mechanism of unequal crossing over following two different modes of misalignment.
    MeSH terms: Base Sequence; DNA Restriction Enzymes; Erythrocytes/metabolism; Fetal Blood; Genes*; Globins/genetics*; Hemoglobins, Abnormal/genetics; Humans; Infant, Newborn; Leukocytes/metabolism; Nucleic Acid Hybridization; Genetic Variation
  2. Wong YC
    Family Practitioner, 1981;4<I> </I>:27-30.
    MeSH terms: Mental Disorders; Depression; Humans; Mass Screening
  3. Wong HB
    Family Practitioner, 1981;4<I> </I>:33-38.
    MeSH terms: Mass Screening
  4. Tweedie DR
    Family Practitioner, 1981;4:79-81.
    MeSH terms: History, 20th Century
  5. Thirumoorthy T
    Family Practitioner, 1981;4<I> </I>:53-54.
    MeSH terms: Dermatology
  6. Teoh SK
    Family Practitioner, 1981;4<I> </I>:23-26.
    MeSH terms: Mass Screening; Obstetrics
  7. Tan FEH
    Family Practitioner, 1981;4<I> </I>:50-51.
  8. Tan CK
    Family Practitioner, 1981;4:43-46.
    MeSH terms: Deafness
  9. Tan CK
    Family Practitioner, 1981;4:29-30.
    MeSH terms: Child; Humans; Malaysia
  10. Tan CK
    Family Practitioner, 1981;4:21-26.
    MeSH terms: Child; Malaysia
  11. Tan CK
    Family Practitioner, 1981;4(1):12-16.
    MeSH terms: Humans
  12. Syed Mahmood SH
    Family Practitioner, 1981;4:3-3.
  13. Suleiman AB
    Family Practitioner, 1981;4:17-18.
    MeSH terms: Mass Screening
  14. Strahm RW
    Family Practitioner, 1981;4(2):27-28.
    MeSH terms: Disabled Persons
  15. Phoon WO
    Family Practitioner, 1981;4:5-10.
    MeSH terms: Child; Malaysia
  16. Ong HC
    Family Practitioner, 1981;4:17-21.
    MeSH terms: Diabetes Mellitus; Pregnancy; Diabetes, Gestational
  17. Ong HC
    Family Practitioner, 1981;4:41-44.
    MeSH terms: Pregnancy; Rheumatic Heart Disease
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