Browse publications by year: 1983

  1. Fujimoto Y, Suzuki Y, Kanaiwa T, Amiya T, Hoshi K, Fujino S
    J. Pharmacobio-dyn., 1983 Feb;6(2):128-35.
    PMID: 6306201
    The present research is on a milky sap obtained from the Antiaris toxicaria tree (Moraceae) which is called Upas or Ipoh in Indonesia. The crude sap was administered to anesthetized rats, and changes in electrocardiogram (ECG) and systemic blood pressure was observed. Biologically and pharmacologically active components were extracted from the crude sap by means of water-acetone solution. Based on the strength of chemical qualitative detection tests of the sap extract (SE), cardiac glycosides are supposed to be the main components. The SE inhibited the Na+-, K+-ATPase (EC which was partially purified from guinea pig heart muscle. When the SE and, concurrently, authentic ouabain were applied to isolated frog heart muscles, the fall of twitch tension was observed after the increased tension on mechanograms. These facts suggest that the main components of the milky sap are cardiac glycosides, and glycosides affect Na+, K+-ATPase activity of muscle membrane and heart muscle contraction.
    MeSH terms: Sodium-Potassium-Exchanging ATPase/metabolism; Animals; Blood Pressure/drug effects; Heart/drug effects; Muscle Contraction/drug effects; Myocardium/enzymology; Plant Extracts/analysis; Plant Extracts/pharmacology; Plant Proteins/analysis; Ranidae; Rats; In Vitro Techniques
  2. Zakriya M
    Family Practitioner, 1983;6:61-62.
    MeSH terms: Rehabilitation
  3. Yong EL, Lim PHC
    Family Practitioner, 1983;6:67-69.
    MeSH terms: Testis; Seminoma
  4. Woon TH
    Family Practitioner, 1983;6(2):55-57.
    With about 1% of Malaysian medical practitioners being psychiatrist, the patients need the psychiatric skill and care of general practitioners for both early referral and follow-up care. The psychological reactions aroused by the mentally ill patients may be jointly managed by the doctors and their families. The primary care doctor can play an effective therapeutic and supporting role in the rehabilitation of the patient that may include, when available, other workers in social and psychiatric services.
    MeSH terms: Physicians; Primary Health Care; Rehabilitation; General Practitioners
  5. Wong HB
    Family Practitioner, 1983;6:23-28.
    MeSH terms: Glucosephosphate Dehydrogenase Deficiency
  6. Wo KT
    Family Practitioner, 1983;6(3):27-28.
    MeSH terms: Humans; Proteinuria
  7. Wang F
    Family Practitioner, 1983;6:23-26.
    MeSH terms: Adult; Infection; Urinary Tract; Urinary Tract Infections
  8. Thuraisingham V
    Family Practitioner, 1983;6:25-27.
    MeSH terms: Coronary Disease; Heart
  9. Thirumoorthy T
    Family Practitioner, 1983;6:47-50.
    MeSH terms: Child; Dermatology; Pediatrics
  10. Thirumoorthy T
    Family Practitioner, 1983;6:69-71.
    MeSH terms: Infection; Sexually Transmitted Diseases
  11. Tan TH
    Family Practitioner, 1983;6(1):11.
    MeSH terms: Periodicals as Topic
  12. Tan CK
    Family Practitioner, 1983;6:67-70.
    MeSH terms: Hospitalization
  13. Syed Mahmood SH
    Family Practitioner, 1983;6<I> </I>:88-89.
  14. Suleiman AB
    Family Practitioner, 1983;6:65-66.
    MeSH terms: Humans; Proteinuria
  15. Saw HS
    Family Practitioner, 1983;6:43-49.
    MeSH terms: Physicians; Physicians, Family; General Practitioners
  16. Robaayah Z
    Family Practitioner, 1983;6:28-29.
    MeSH terms: Hypertension
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