Browse publications by year: 2005

  1. College of Pathologists, Academy of Medicine of Malaysia
    Malays J Pathol, 2005 Jun;27(1):57-62.
    PMID: 16676695
    MeSH terms: Education, Professional/standards*; Humans; Laboratories*; Malaysia; Pathology/education*; Pathology/standards; Professional Competence*; Guidelines as Topic
  2. College of Pathologists, Academy of Medicine of Malaysia
    Malays J Pathol, 2005 Jun;27(1):63-7.
    PMID: 16676696
    MeSH terms: Facility Design and Construction*; Humans; Interior Design and Furnishings/standards*; Laboratories/standards*; Malaysia; Guidelines as Topic
  3. College of Pathologists, Academy of Medicine of, Malaysia
    Malays J Pathol, 2005 Jun;27(1):69-70.
    PMID: 16676697
    MeSH terms: Equipment and Supplies; Humans; Laboratories/organization & administration*; Maintenance/methods*; Malaysia; Pathology; Guidelines as Topic; Clinical Laboratory Techniques/instrumentation*
  4. College of Pathologists, Academy of Medicine of, Malaysia
    Malays J Pathol, 2005 Jun;27(1):71-2.
    PMID: 16676698
    MeSH terms: Humans; Laboratories/standards*; Malaysia; Pathology; Hazardous Substances/standards*; Medical Laboratory Personnel/education*; Guidelines as Topic; Safety Management/organization & administration*
  5. College of Pathologists, Academy of Medicine of, Malaysia
    Malays J Pathol, 2005 Jun;27(1):73-4.
    PMID: 16676699
    MeSH terms: Humans; Laboratories/standards*; Malaysia; Pathology; Specimen Handling/standards*; Guidelines as Topic
  6. Schilthuizen M
    Trends Ecol Evol, 2005 Nov;20(11):581-4.
    PMID: 16701439
    Love darts are hard 'needles' that many snails and slugs use to pierce their partner during mating. In a few species, darts have been shown to play a role in sperm competition. Two new papers, by Davison et al., and Koene and Schulenburg, might further pique researchers' interest, because they show how the full potential of darts can be tapped for studies of sexual selection in hermaphrodites.
    MeSH terms: Animals; Humans; Love; Male; Reproduction; Disorders of Sex Development; Sexual Partners; Snails; Spermatozoa
  7. Am J Ophthalmol, 2005 Apr;139(4 Suppl):S1-71.
    PMID: 16729358
    MeSH terms: Animals; Eye Diseases*; Humans; Ophthalmology*; Vision, Ocular*
  8. Lee YW, Zairi J
    Trop Biomed, 2005 Jun;22(1):5-10.
    PMID: 16880748
    Laboratory efficacy and residual activity of a water dispersible granule formulation of Bacillus thuringiensis israelensis (Bti) at the dosages of 3000, 6000 and 15000 ITU/L were conducted in this study. The study was conducted in two different size containers, earthen jar (45 L) and glass jar (3 L) with or without daily replenishment of 6 L and 0.3 L of water in the earthen and glass jars, respectively. Results indicate that for both earthen jar and glass jar evaluations, Bti at the tested dosages, performed effectively against Aedes aegypti, giving a minimum of 42 days effective killing activity. When the dosage was increased from 3000 ITU/L to 6000 ITU/L or 15000 ITU/L, the effective periods of the Bti increased by an additional one to three weeks. The Bti water dispersible granule provided better larvicidal activity with replenishment of water compared with non-replenishment of water especially for the higher dosage (15000 ITU/L).
    MeSH terms: Aedes/drug effects*; Animals; Bacillus thuringiensis*; Insect Vectors/drug effects; Insecticides/pharmacology*; Pest Control, Biological*; Water
  9. Anisah N, Amal H, Kamel AG, Yusof S, Noraina AR, Norhayati M
    Trop Biomed, 2005 Jun;22(1):11-4.
    PMID: 16880749 MyJurnal
    Is Acanthamoeba sp. normally found in the eyes? A study was carried out to establish the possibility of Acanthamoeba sp. as a part of the normal conjunctival flora. Conjunctiva swabbing were carried out in 286 healthy Orang Asli school children using sterile cotton swab. The swab was then inoculated onto non-nutrient agar (NN-A). Heat killed Escherichia coli that was used as food source for the growth of the amoebae was pipetted onto and away from the smear. The plates were incubated at 30 degrees C and examined daily using an inverted microscope for 14 days. Morphology of the trophozoites and cysts of the amoebae were used as the taxonomic criteria for identification. Positive-controls and negative-controls were done to check for the consistency of the technique used and monitoring of contamination respectively. None of the conjunctiva swab cultured was positive for Acanthamoeba sp. This finding may indicate that Acanthamoeba sp. is not part of normal conjunctival flora or conjunctiva swab is an insensitive technique to isolate the organism. However, a more extensive research is needed to investigate these possibilities.
    MeSH terms: Acanthamoeba/isolation & purification*; Amebiasis/diagnosis*; Amebiasis/microbiology; Amebiasis/pathology; Animals; Child; Conjunctiva/microbiology*; Conjunctivitis/diagnosis*; Conjunctivitis/microbiology; Conjunctivitis/pathology; Humans; Predictive Value of Tests; Specimen Handling/instrumentation; Cotton Fiber
  10. Nadchatram M
    Trop Biomed, 2005 Jun;22(1):23-37.
    PMID: 16880751
    House dust mites have lived in human contact from time immemorial. Human dander or dead skin constitutes the major organic component of the house dust ecosystem. Because the mites feed on dander, dust mites and human association will continue to co-exist as part of our environment. Efficient house-keeping practice is the best form of control to reduce infestation. However, special precautions are important when individuals are susceptible or sensitive to dust mites. House dust mites are responsible for causing asthma, rhinitis and contact dermatitis. The respiratory allergies are caused by the inhalation of dead or live mites, their faecal matter or other byproducts. Immune factors are of paramount importance in the development of dust related or mite induced respiratory diseases. House dust mites were found in some 1,000 samples of dust taken from approximately 330 dwellings in Peninsular Malaysia and Singapore. Mattresses, carpets, corners of a bedroom, and floor beneath the bed are favourable dust mite habitats. The incriminating species based on studies here and elsewhere, as well as many other species of dust mites of unknown etiological importance are widely distributed in Malaysian homes. Density of dust mites in Malaysia and Singapore is greater than in temperate countries. Prevention and control measures with reference to subjects sensitive to dust mite allergies, including chemical control described in studies conducted in Europe and America are discussed. However, a cost free and most practical way to remove mites, their faecal matter and other products is to resort to sunning the bedding and carpets to kill the living mites, and then beaten and brushed to remove the dust and other components.
    MeSH terms: Allergens/adverse effects*; Animals; Dust*; Environmental Exposure; Household Articles; Housing*; Humans; Respiratory Tract Diseases/etiology; Respiratory Tract Diseases/prevention & control*; Dermatophagoides pteronyssinus*
  11. Chen CD, Benjamin S, Saranum MM, Chiang YF, Lee HL, Nazni WA, et al.
    Trop Biomed, 2005 Jun;22(1):39-43.
    PMID: 16880752
    Ovitrap surveillance was conducted in two urban residential areas (Taman Samudera Timur and Taman Samudera Selatan) and in a settlement area (Kampung Banjar), which is located 16 km from Kuala Lumpur city center, Malaysia. In Taman Samudera, dengue cases were reported monthly in 2003/2004. Thus, a study was initiated to determine the distribution and abundance of dengue vectors, Aedes aegypti and Ae. albopictus. The ovitrap surveillance indicated that Ae. aegypti and Ae. albopictus were present both indoors and outdoors. The residential sites had 73 - 79% of the ovitraps with just Ae. aegypti population and Kg. Banjar had 56% of the ovitraps with just Ae. aegypti. In the indoor and outdoor of the residential areas, together with the settlement area, the Ae. aegypti density was significantly more than Ae. albopictus (p < 0.05) by 3 - 50 folds. There was no significant difference in the larval numbers of Ae. aegypti between indoors and outdoors (p > 0.05), thus implicating that adult gravid female Ae. aegypti are present both indoors and outdoors and they do oviposit indoors and outdoors. Ae. aegypti can be incriminated as the principal dengue vector in the urban residential site, Taman Samudera and in the settlement area, Kg. Banjar.
    MeSH terms: Aedes*; Animals; Dengue/etiology; Dengue/epidemiology*; Dengue/prevention & control; Dengue/transmission*; Housing; Humans; Insect Vectors*; Malaysia/epidemiology; Mosquito Control; Population Density; Seasons; Urban Health
  12. Hamdan H, Sofian-Azirun M, Nazni W, Lee HL
    Trop Biomed, 2005 Jun;22(1):45-52.
    PMID: 16880753
    Laboratory-bred females of Culex quinquefasciatus, Aedes aegypti and Aedes albopictus from the insectarium, Unit of Medical Entomology, Institute for Medical Research were used in the experiment. The late third stage of the F0 larvae which survived the high selection pressure of malathion, permethrin and temephos were reared and colonies were established from adults that emerged. Cx. quinquefasciatus larvae were subjected to selection by malathion and permethrin for 40 generations, Ae. aegypti larvae to malathion, permethrin and temephos for 32 generations and Ae. albopictus larvae were selected against malathion and permethrin for 32 generations and 20 generations against temephos. The rate of resistance development was measured by LC50 value. Cx. quinquefasciatus larvae developed higher resistance to malathion and permethrin compared to Ae. aegypti and Ae. albopictus. On the whole, permethrin resistance developed at a faster rate than malathion and temephos.
    MeSH terms: Temefos/pharmacology; Aedes/drug effects*; Animals; Culex/drug effects*; Insecticide Resistance*; Insecticides/pharmacology*; Larva/drug effects; Lethal Dose 50; Malathion/pharmacology; Permethrin/pharmacology
  13. Nazni WA, Luke H, Wan Rozita WM, Abdullah AG, Sa'diyah I, Azahari AH, et al.
    Trop Biomed, 2005 Jun;22(1):53-61.
    PMID: 16880754
    In order to control any pest it is essential to study the life cycle, biology and bionomics of the target pest under control. With this respect, we have studied the flight range of the house fly Musca domestica (L.). The flight range of the house fly from two sites i.e, the poultry farm and a stable farm has been studied. The flight range study was conducted using a mark release technique. The approach we used in this study was that the flies collected from the respective farms were marked and released at different distances from the farms. The flies were then re-captured from the poultry farm and the stable farm. Studies conducted elsewhere use the technique of releasing the insect species at one spot and recapturing the insect species with the help of baited traps placed at various locations from the release point. The advantage of the approach used in this study was that the flight range as well as the homing effect was determined. From this study, the flight range of house flies released at the poultry farm was 7 km whereas flight range for flies release from stable farm was 5 km. The recovery rate of house flies at the poultry and stable farm was 0.05% and 0.016%, In this study, marked specimens has been detected up to 8 days in field conditions indicating that under field condition the life expectancy could be in the range of 1-2 weeks.
    MeSH terms: Agriculture; Animals; Behavior, Animal*; Houseflies*; Insect Control/methods*; Population Density
  14. Nazni WA, Lee HL, Azahari AH
    Trop Biomed, 2005 Jun;22(1):63-8.
    PMID: 16880755 MyJurnal
    The susceptibility of Culex quinquefasciatus to chemical insecticides in two field sites in Kuala Lumpur was evaluated using the WHO standard susceptibility test. Less then 7 days old female mosquitos, reared from wild caught females were exposed to discriminating dosages of insecticides at recommended exposure periods. The larval bioassay were conducted using the multiple concentrations and the LC50 value was determined. The results indicated that cyfluthrin is the most effective among all the insecticides tested with LT50 value of 29.95 min and 28.59 min, for the strain from Ampang Hill and Pantai Dalam, respectively. It was surprisingly to note that both these field strains showed 0% mortality when tested against malathion and DDT. The LC50 value indicated that both strains were highly resistant to malathion with resistance ratio of 17,988 folds and 14,053 folds, respectively. This concludes that resistance at larval stages is extremely high compared to adult stages.
    MeSH terms: Animals; Culex/drug effects*; DDT/pharmacology; Female; Insecticide Resistance*; Insecticides/pharmacology*; Larva/drug effects; Lethal Dose 50; Malathion/pharmacology; Mosquito Control
  15. Ooi CP, Rohani A, Zamree I, Chua WS
    Trop Biomed, 2005 Jun;22(1):69-71.
    PMID: 16880756 MyJurnal
    Artificial feeding of mosquitoes with blood meal is an important technique in the studies of mosquito feeding. Owing to the difficulty in obtaining suitable artificial membranes for mosquito feeding from other sources, several easily obtainable membranes in Malaysia were tested for their suitability as a replacement. Skin of chicken, fish, and salted sausage were obtained and tested against cattle skin membrane as a control. The results showed that cattle skin is still the most favorable membrane to be used, with full engorgement rate of around 57% using fresh human blood. However, processed chicken skin was shown having potential for further testing since with feeding using human blood kept overnight at 4 degrees C, an engorgement rate of 50% was obtained.
    MeSH terms: Aedes*; Animals; Cattle; Chickens; Feeding Behavior*; Female; Meat
  16. Ooi CP, Rohani A, Zamree I, Lee HL
    Trop Biomed, 2005 Jun;22(1):73-6.
    PMID: 16880757
    The rapid detection of dengue infection in mosquito vectors is important for early warning to forestall an outbreak. Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) provides a rapid method for dengue detection in man and mosquitoes. An RT-PCR kit developed by the Medical Entomology Unit, Institute for Medical Research to detect dengue infection in mosquitoes, was tested for its shelf life at 3 storage temperatures: room temperature, refrigerator and freezer. Test kits were tested once every 3 days for kits stored at room temperature, and once every week for those stored at refrigerator and freezer temperatures. The results showed that the test kit could only be stored above its recommended storage temperature of -20 degrees C for not more than 3 days. DNA 100 bp markers in the kits appeared to be stable at the tested temperatures and were usable up to the 20th day when stored at 2 degrees C and below.
    MeSH terms: Animals; Dengue/diagnosis*; Dengue/prevention & control; Dengue/virology; Dengue Virus/genetics; Dengue Virus/isolation & purification*; Drug Storage; Humans; Insect Vectors/virology*; Culicidae/virology*; Predictive Value of Tests; Reagent Kits, Diagnostic*; RNA, Viral/analysis; Temperature; Reverse Transcriptase Polymerase Chain Reaction
  17. Vythilingam I, Sidavong B, Seng TC, Phonemixay T, Phompida S, Krishnasamy M
    Trop Biomed, 2005 Jun;22(1):77-9.
    PMID: 16880758
    Unidentified mermithid nematodes were found in the abdominal cavity of three species of Anopheles mosquitoes from LAO PDR. This is a first record of mermithid nematodes in adult mosquitoes from Lao PDR. Two worms were found in each adult host and the infection was more prevalent in the northern region compared to the south.
    MeSH terms: Animals; Laos; Mosquito Control; Culicidae/parasitology*; Nematoda/classification; Nematoda/isolation & purification*
  18. Lee HL, Krishnasamy M, Jeffery J
    Trop Biomed, 2005 Jun;22(1):81-2.
    PMID: 16880759 MyJurnal
    The hornets are a group of venomous stinging insects that at times cause human death. A fatal case of a child stung by the lesser banded hornet Vespa affinis indosinesis is reported. Though often covered by the mass media, this constitutes the first scientifically reported case.
    MeSH terms: Anaphylaxis/diagnosis*; Anaphylaxis/pathology; Animals; Child; Diagnosis, Differential; Humans; Insect Bites and Stings/diagnosis*; Insect Bites and Stings/pathology; Malaysia; Male; Wasps*; Fatal Outcome
  19. Vythilingam I, Tan CH, Nazni WA
    Trop Biomed, 2005 Jun;22(1):83-5.
    PMID: 16880760 MyJurnal
    Laboratory strain of the Malaysian Culex quinquefasciatus was susceptible to Wuchereria bancrofti. Thirty three percent of the Cx. quinquefasciatus that fed on W. bancrofti patient were infective after 12-14 days. There is a possibility for W. bancrofti to occur in the urban areas of the Malaysia in the near future.
    MeSH terms: Animals; Culex/parasitology*; Diagnosis, Differential; Filariasis/diagnosis*; Filariasis/transmission; Humans; Insect Vectors/parasitology*; Insecticide Resistance; Malaysia; Urban Health; Wuchereria bancrofti/genetics; Wuchereria bancrofti/isolation & purification*; Polymerase Chain Reaction; DNA, Helminth/analysis
  20. Lee HL, Krishnasamy M, Jeffery J
    Trop Biomed, 2005 Jun;22(1):87-8.
    PMID: 16880761
    MeSH terms: Aged; Aged, 80 and over; Animals; Diagnosis, Differential; Diptera*; Female; Humans; Malaysia; Myiasis/diagnosis*; Myiasis/parasitology; Nasopharyngeal Diseases/diagnosis*; Nasopharyngeal Diseases/parasitology
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