Affiliations 

  • 1 Gastroenterology, Hôpital Européen Georges Pompidou, France
  • 2 Asian Institute of Gastroenterology
  • 3 Surgery, Universiti Kebangsaan Malaysia
  • 4 Interventional Radiology, Universiti Kebangsaan Malaysia
  • 5 Gastroenterology, Hôpital Européen Georges Pompidou
  • 6 Gastroenterology, Georges-Pompidou European Hospital, Francia
  • 7 Gastroenterology, Georges-Pompidou European Hospital, France
Rev Esp Enferm Dig, 2022 Jan 11.
PMID: 35012320 DOI: 10.17235/reed.2022.8451/2021

Abstract

Introduction Biodegradable stents of various designs are reportedly used in pancreato-biliary conditions with promising results. Their major advantage is the avoidance of a repeat endoscopic procedure for stent removal thereby reducing overall cost along with ERCP associated adverse events. To evaluate the feasibility and safety of a new biodegradable stent in patients with pancreato-biliary diseases. Methods Prospective multicenter pilot study. All consecutive patients 18 years-old who underwent biliary or pancreatic stenting using the new biodegradable Archimedes stent were included. There were three biodegradation profiles. Technical and clinical success, feasibility and safety were assessed during a pre-established follow-up schedule. Results Fifty-three patients (mean age: 48.54±19.29, 66% male) having biliary (n=29, 54.7%%) or pancreatic (n=24, 45.3%) indications were included. The distribution of stents used according to degradation properties were as follows: fast (n=11, 20.8%), medium (n=16, 30.2%) and slow (n=26, 49.1%). The technical and clinical success were 100% and 77.8%. Thirty-five patients were followed for a median of 26 weeks (range: 4-56, 66%). There were 9 procedure-related adverse events (17%), all mild, including one uneventful stent-related event (external migration). Conclusion The biodegradable Archimedes stent placement is feasible and safe in pancreato-biliary diseases.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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