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Evaluation of interleukin-1β and 8 in gutka chewers with periodontitis among a rural Indian population

Jacob PS 1 , Nath S 2 , Patel RP 3

Affiliations 

  • 1 Department of Clinical Dentistry, International Medical University School of Dentistry, Kuala Lumpur, Malaysia
  • 2 Department of Periodontology, Vananchal Dental College and Hospital, Garhwa, India
  • 3 Department of Periodontology, Chhattisgarh Dental College and Research Institute, Rajnandgaon, India
J Periodontal Implant Sci, 2014 Jun;44(3):126-33.
PMID: 24921056 DOI: 10.5051/jpis.2014.44.3.126

Abstract

Smokeless tobacco-based oral-use products like gutka are popular in India. Gutka usage leads to increased periodontal destruction and inflammation; however, the relevant mechanism remains unknown. This study aimed to elucidate the role of gutka in periodontitis by examining its effect on the levels of interleukin (IL) 1β and IL-8 from the gingival crevicular fluid (GCF).

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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