Affiliations 

  • 1 Department of Periodontology and Oral Implantology, Tamilnadu Government Dental College, Chennai, India
  • 2 Department of Restorative Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia
  • 3 Department of Periodontology and Oral Implantology, Vananchal Dental College, Jharkhand, India
Open Dent J, 2016;10:174-81.
PMID: 27386002 DOI: 10.2174/1874210601610010174

Abstract

Periodontitis is a chronic bacterial infection resulting in destruction of the supporting structures of the teeth. Regeneration of the lost tissues has faced difficulties primarily due to the lack of support during the intricate healing processes. A surgical additive which can 'jump start' the healing process to a more predictable regenerative process is always on the wish list of any periodontist. Platelet-rich fibrin (PRF) is a second generation platelet concentrate that has been considered to be an important, easy to obtain, predictable surgical additive for periodontal regeneration. This autologous scaffold provides the much needed bio-chemical mediators which has the potential for enhancing reconstruction of the periodontium. This review article tries to understand as to why PRF would be an important link to reach predictable periodontal regeneration.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.