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Threshold conditions for global stability of disease free state of COVID-19

Zamir M 1 , Shah K 2 , Nadeem F 1 , Bajuri MY 3 , Ahmadian A 4 , Salahshour S 5 Show all authors , Ferrara M 6

Affiliations 

  • 1 Department of Mathematics, University of Science and Technology, Bannu, Khyber Pakhtunkhwa, Pakistan
  • 2 Department of Mathematics, University of Malakand, Chakdara, Dir(L), Khyber Pakhtunkhwa, Pakistan
  • 3 Department of Orthopaedics and Traumatology, Faculty of Medicine, Universiti Kebangsaan Malaysia(UKM), Kuala Lumpur, Malaysia
  • 4 Institute of IR 4.0, The National University of Malaysia, 43600, UKM, Bangi, Malaysia
  • 5 Faculty of Engineering and Natural Sciences, Bahcesehir University, Istanbul, Turkey
  • 6 ICRIOS - The Invernizzi Centre for Research in Innovation, Organization, Strategy and Entrepreneurship, Bocconi University, Department of Management and Technology Via Sarfatti, 25 20136 Milano (MI), Italy
Results Phys, 2021 Feb;21:103784.
PMID: 36465528 DOI: 10.1016/j.rinp.2020.103784

Abstract

This article focus the elimination and control of the infection caused by COVID-19. Mathematical model of the disease is formulated. With help of sensitivity analysis of the reproduction number the most sensitive parameters regarding transmission of infection are found. Consequently strategies for the control of infection are proposed. Threshold condition for global stability of the disease free state is investigated. Finally, using Matlab numerical simulations are produced for validation of theocratical results.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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