Affiliations 

  • 1 Phytochemistry and National Products Department, Technical Office of Central Administration of Drug Control, Egyptian Drug Authority (EDA), Giza 12553, Egypt
  • 2 Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia
  • 3 Pharmacognosy Department, College of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo 11562, Egypt
ACS Omega, 2022 Dec 20;7(50):45797-45809.
PMID: 36570239 DOI: 10.1021/acsomega.2c04708

Abstract

Herbal cigarettes, known as tobacco-free or nicotine-free cigarettes, are those recognized as being-tobacco free, being composed of a mixture of various herbs claimed to lessen the smoking habit hazards. However, controversial data regarding its properties occur in the literature with no comprehensive overview or analysis of its effects. Like herbal smokeless tobacco, they are often used to substitute for tobacco products (primarily cigarettes) regarded as a "nonsmoking" aid. This review capitalizes on herbal cigarettes with regard to their quality characteristics, sensory attributes, chemical composition, and health properties to rationalize their choice as a nonsmoking aid. Furthermore, the impacts of heat and/or pyrolysis that occur during smoking on its chemical composition are presented for the first time. Some herbal smokes may produce notable metabolic problems that increase the risk of several chronic metabolic diseases. In general, burning substances from plants can have a variety of negative effects on the body attributed to toxic chemicals such as carbon monoxide, polyaromatics, nicotine, and N-nitrosamines. This review compiles and discusses the phytochemical compositions detected in various herbal cigarettes alongside sensory and quality attributes and health effects.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.