Affiliations 

  • 1 Solid State Department, Physics Division, National Research Centre, Dokki, Giza, Egypt
  • 2 Pesticide Chemistry Department, National Research Centre, Dokki, Giza 12622, Egypt
  • 3 Physics Department, Faculty of Science, Helwan University, Helwan, Cairo, Egypt
  • 4 Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
Acta Crystallogr Sect E Struct Rep Online, 2014 Jan 01;70(Pt 1):o22-3.
PMID: 24855467 DOI: 10.1107/S1600536813032765

Abstract

The title compound, C30H28ClN3O2, features two spiro links, one connecting the piperidine and pyrrolidine rings, and the other connecting the pyrrolidine ring and indole residue. The configuration about the ethene bond is E. The piperidine ring adopts a half-chair conformation where the C atom connected to the spiro-C atom lies 0.713 (3) Å out of the plane of the remaining five atoms (r.m.s. deviation = 0.086 Å). The pyrrolidine ring has an envelope conformation with the flap atom being the methyl-ene C atom. Centrosymmetric eight-membered {⋯HNCO}2 amide synthons feature in the crystal packing. These are consolidated into a three-dimensional architecture by phen-yl-pyrrolidine C-H⋯N and chloro-benzene-pyrrolidine-bound phenyl C-H⋯π inter-actions.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.