Determinants of microalbuminuria among type 2 diabetes mellitus patients in Kuala Selangor district: A cross-sectional study

Shahrir NF 1 , Aziz NRA 2 , Ahmad FL 3 , Muzaid NA 4 , Samat F 5 , Syed Ghazaili SNA 6 Show all authors , Dolbasir N 7 , Baharum NN 8 , T Ramanathan S 9 , Abd Rahman SZ 10 , Bat AS 11 , Sarif M 12 , Ismaal NA 13

Affiliations 

  • 1 MBBS (UiTM), MPH, DrPH (USM) Pejabat Kesihatan Daerah Kuala, Selangor, Jalan Semarak, Bandar, Melawati, Kuala Selangor, Malaysia. Email: pare87_me@yahoo.com
  • 2 MBBS (UM), MPH (USM) Pejabat Kesihatan Daerah Kuala, Selangor, Jalan Semarak, Bandar, Melawati, Kuala Selangor, Malaysia
  • 3 MD(UKM) Pejabat Kesihatan Daerah Kuala, Selangor, Jalan Semarak, Bandar, Melawati, Kuala Selangor, Malaysia
  • 4 MD(UKM) MMed(Family Medicine) (UKM) Klinik Kesihatan Kuala Selangor, Jalan Klinik, Bandar Malawati, Kuala, Selangor, Malaysia
  • 5 MD(UKM) MMed (Family Medicine) UiTM, Klinik Kesihatan Tanjong karang, Kuala Selangor, Malaysia
  • 6 MD(UKM) MMed (Family Medicine) (USM) Klinik Kesihatan Bestari Jaya, Bestari Jaya, Malaysia
  • 7 MD (UKM), MMed (Family Medicine) (UM) Klinik Kesihatan Jeram, Jalan Klang-Telok Intan, Jeram, Malaysia
  • 8 MBBS (IIUM), MMed (Family Medicine) (UiTM) Klinik Kesihatan Bukit Cherakah, Jalan Rizab Masjid, Jeram, Malaysia
  • 9 MBBS (MAHE,MANIPAL)(FRACGP/MAFP) Klinik Kesihatan Ijok, JKR 1087, Jalan 14, Ijok, Batang Berjuntai, Malaysia
  • 10 MBBS (CUCMS) Klinik Kesihatan Sg. Tengi Kanan, Jalan Kiai Moid, Tanjong Karang, Malaysia
  • 11 MD (USU) Klinik Kesihatan Bukit Cherakah, Jln Rizab Masjid, Kg. Bukit Cherakah, Jeram, Malaysia
  • 12 Diploma Kejururawatan, Klinik Kesihatan Bukit Cherakah, Jln Masjid, Jeram, Malaysia
  • 13 Diploma Kejururawatan, Klinik kesihatan Sg Tengi Kanan, Jalan Kiai Moid, Tanjung Karang, Malaysia
Malays Fam Physician, 2022 Nov 30;17(3):53-63.
PMID: 36606172 DOI: 10.51866/oa.122

Abstract

INTRODUCTION: Microalbuminuria presents significant health risks for the progression of endstage renal-failure (ESRF) among type 2 diabetes mellitus (T2DM) patients. This study aims to determine the proportion and associated factors of microalbuminuria among T2DM patients in Kuala Selangor district, Malaysia.

METHOD: A retrospective cross-sectional study was conducted from December 2020 to February 2021 using secondary data from the National Diabetic Registry (NDR), Malaysia, and reviewed patients' diabetic records for the year 2020. All T2DM patients aged >18 years who were registered with the NDR in 2020 and fulfilled the inclusion and exclusion criteria were included in the study. Descriptive statistics and multiple logistic regression analysis were performed. Data were analysed using SPSS version 26.0. A total of 343 samples were included in this study for the determination of the proportion of microalbuminuria and its associated factors.

RESULTS: Of 343 respondents, 34.4% had microalbuminuria. HbAlc >7.0% (AdjOR 2.19, 95% CI: 1.35, 3.55, p=0.001), HDL <1.04 mmol/L (AdjOR 2.44, 95% CI: 1.323, 4.52, p=0.004), dyslipidaemia (AdjOR 1.90, 95% CI: 1.03, 3.48, p=0.039), and peripheral neuropathy (AdjOR 3.01, 95% CI: 1.02, 8.93, p=0.047) were significantly associated with microalbuminuria. Conclusion: Microalbuminuria is a modifiable risk factor in preventing the progression of ESRF among T2DM patients. Therefore, identification of factors associated with microalbuminuria among this high-risk group is important to facilitate early screening and prompt treatment to prevent progression of diabetic kidney disease to ESRF.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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