Comparison of outcome among type 2 vs type 1 myocardial infarction: a systematic review and meta-analysis

Jaiswal V 1 , Ang SP 2 , Ishak A 3 , Nasir YM 4 , Chia JE 5 , Naz S 6 Show all authors , Jaiswal A 7

Affiliations 

  • 1 Division of Cardiovascular Research, Larkin Community Hospital, South Miami, FL, USA
  • 2 Department of Internal Medicine, Rutgers Health/Community Medical Center, NJ, USA
  • 3 School of Medicine, European University Cyprus, Nicosia, Cyprus
  • 4 Division of Internal Medicine, Montefiore Medical Center, New York, NY, USA
  • 5 School of Medicine, International Medical University, Kuala Lumpur, Malaysia
  • 6 Division of Internal Medicine, BIDMC, Harvard Medical School, Boston, MA, USA
  • 7 Department of Geriatric Medicine, All India Institute of Medical Science, New Delhi, India
J Investig Med, 2023 Mar;71(3):223-234.
PMID: 36705027 DOI: 10.1177/10815589221140589

Abstract

To date, there were limited studies available on myocardial infarction (MI), and consequently, the outcomes of patients with type 1 myocardial infarction (T1MI) compared to type 2 myocardial infarction (T2MI) remained inconclusive. We aimed to compare the outcomes of T1MI and T2MI patients in terms of mortality and adverse cardiovascular outcomes. We performed a systematic literature search on PubMed, Embase, and Scopus for relevant articles from inception until March 20, 2022. 341,049 patients had T1MI, while the remaining 67,537 patients had T2MI. Mean age was similar between both groups (T1MI: 67.3 years, T2MI: 71.03 years), while the proportion of females was lower in T1MI (37.81% vs 47.15%). Our analysis revealed that patients with T1MI had significantly lower odds of all-cause mortality (OR 0.45, 95% CI 0.36-0.56, p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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