Affiliations 

  • 1 Green Analytical Chemistry Laboratory, School of Chemical Sciences, Universiti Sains Malaysia, 11800 Minden, Pulau Pinang, Malaysia; Department of Chemistry and Industrial Chemistry, Kwara State University, Malete, P.M.B 1530 Ilorin, Nigeria
  • 2 Green Analytical Chemistry Laboratory, School of Chemical Sciences, Universiti Sains Malaysia, 11800 Minden, Pulau Pinang, Malaysia. Electronic address: fsuah@usm.my
Int J Biol Macromol, 2023 Jun 30;241:124610.
PMID: 37116836 DOI: 10.1016/j.ijbiomac.2023.124610

Abstract

The aggressive search for unique materials in recent years has put forward chitosan and modified-chitosan as materials with unique structural and morphological characteristics for various important applications. Just as imidazolium-based ionic liquids are the commonly applied ionic liquids (ILs) type for chitosan modifications for various applications, their further modifications into beads for enhancing their properties is now gaining most attention. However, most of the currently prepared imidazolium ILs modified-chitosan beads are not in nano size due to preparation difficulties. In response to this and referencing the research works in the literature, the possible breakthrough directions including synthesis routes, and physical and mechanical transformation processes are proposed. These procedures are expected to provide certain theoretical and empirical basis, as well as technical guide for developing nano-micro size chitosan beads using imidazolium based ILs.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.