Affiliations 

  • 1 Department of Prosthodontics, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India
  • 2 Consultant Oral and Maxillofacial Surgeon, Ahmedabad, Gujrat, India
  • 3 Department of Prosthodontics, Kalinga Institute of Dental Sciences, KIIT University, Patia, Bhubaneswar, Odisha, India
  • 4 Private Practitioner, SMS Dental Hospital, Visakhapatnam, Andhra Pradesh, India
  • 5 Department of Oral and Maxillofacial Surgery and Diagnostic Science, Taif University, Taif, Saudi Arabia
  • 6 Department of Periodontics, Faculty of Dentistry, AIMST University, Semeling, Bedong, Kedah, Malaysia
J Pharm Bioallied Sci, 2023 Jul;15(Suppl 1):S183-S186.
PMID: 37654403 DOI: 10.4103/jpbs.jpbs_449_22

Abstract

INTRODUCTION: In many oral procedures that involve the implants, hair implantations, "Platelet-Rich Fibrin Membrane (PRF)" is commonly applied. The advantages are many. In this study, the mechanical resistance of PRF under resistance pull on a longitudinal axis was assessed and compared.

MATERIAL AND METHODS: For the current in vitro study, 60 volunteers donated each 10 ml of their blood and hence a total volume of 600 ml of blood was procured that was analyzed for the current study. The total volume was grouped to three groups where they receive three resistance centrifugation forces of "F-200,600,800 m/s²." In each group, 20 samples were tested for each level of the G-resistance. Each group was further divided as two subgroups of different times of wait, where they were centrifuged at baseline time and after a stand of 30 minutes. On universal testing equipment, the PRF membranes were mechanically tensioned in order to determine each membrane's resistance force. These values were compared for any statistical variance using appropriate statistical tools keeping P < 0.05.

RESULTS: Any applied force had no statistically significant effect on the centrifugation duration for membrane resistance. When the resistance was applied for the PRP samples immediately after they were procured, no significant variation was seen at all the grades of the centrifugation forces; consequently, the T30 group showed a statistically significant variance for the centrifugation forces applied (P = 0.04), with the highest value when the greatest force was applied. According to the results, the centrifugation waiting period could be determined based on the application requirement.

CONCLUSION: For immediate membrane usage, the centrifugation had no effect on resistance; however, after 30 minutes, a membrane with greater resistance was produced by applying more force.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.