Affiliations 

  • 1 Department of Psychiatry, Hospital Universiti Sains Malaysia, Kota Bharu, MYS
  • 2 Department of Radiology, Hospital Universiti Sains Malaysia, Kota Bharu, MYS
  • 3 Department of Psychiatry, Universiti Sains Malaysia School of Medical Sciences, Kota Bharu, MYS
Cureus, 2023 Oct;15(10):e46670.
PMID: 37942372 DOI: 10.7759/cureus.46670

Abstract

This article discusses the case of an adult woman with comorbid major depressive disorder (MDD) and obsessive-compulsive disorder (OCD). Due to her poor response to initial treatment regimens, a brain computed tomography (CT) was performed, revealing mega cisterna magna (MCM). Subsequently, she responded well to the addition of lorazepam, a benzodiazepine, along with fluvoxamine and quetiapine XR. The clinical significance of MCM and MDD-OCD remains partially understood. Thus, this case report aims to contribute to the literature and review the treatment of benzodiazepines in relation to MCM, MDD, and OCD comorbidities.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.