Affiliations 

  • 1 Department of Surgery, Pusat Perubatan Universiti Kebangsaan Malaysia, 56000, Kuala Lumpur, Malaysia
  • 2 Department of Surgery, Pusat Perubatan Universiti Kebangsaan Malaysia, 56000, Kuala Lumpur, Malaysia. looguohou@ukm.edu.my
  • 3 Department of Internal Medicine, Pusat Perubatan Universiti Kebangsaan Malaya, 59100, Kuala Lumpur, Malaysia
Sci Rep, 2024 Jan 05;14(1):614.
PMID: 38182725 DOI: 10.1038/s41598-024-51384-1

Abstract

Obesity and type 2 diabetes mellitus (T2DM) is an alarming problem globally and a growing epidemic. Metabolic surgery has been shown to be successful in treating both obesity and T2DM, usually after other treatments have failed. This study aims to compare Roux-Y gastric bypass and sleeve gastrectomy in determining early diabetic outcomes in obese Malaysian patients with T2DM following surgery. A total of 172 obese patients with T2DM who were assigned to either laparoscopic Roux-en-Y gastric bypass (LRYGB) or laparoscopic sleeve gastrectomy (LSG) were analysed up to a year post-procedure. The patients' T2DM severity were stratified using the Individualized Metabolic Surgery (IMS) score into mild, moderate and severe. Remission rates of diabetes were compared between surgical techniques and within diabetic severity categories. T2DM remission for patients who underwent either surgical technique for mild, moderate or severe disease was 92.9%, 56.2% and 14.7% respectively. Both surgical techniques improved T2DM control for patients in the study. Comparing baseline with results 1 year postoperatively, median HbA1c reduced from 7.40% (IQR 2.60) to 5.80% (IQR 0.80) (p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.