Differentiation capacity of mouse dental pulp stem cells into osteoblasts and osteoclasts

Kermani S 1 , Megat Abdul Wahab R 2 , Zarina Zainol Abidin I 1 , Zainal Ariffin Z 3 , Senafi S 1 , Hisham Zainal Ariffin S 1

Affiliations 

  • 1 School of Biosciences and Biotechnology, Faculty of Science and Technology, University Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia
  • 2 Department of Orthodontics, Faculty of Dentistry, University Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia
  • 3 School of Biology, Faculty of Applied Sciences, University Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
Cell J, 2014 Feb 3;16(1):31-42.
PMID: 24518973

Abstract

Our research attempted to show that mouse dental pulp stem cells (DPSCs) with characters such as accessibility, propagation and higher proliferation rate can provide an improved approach for generate bone tissues. With the aim of finding and comparing the differentiation ability of mesenchymal stem cells derived from DPSCs into osteoblast and osteoclast cells; morphological, molecular and biochemical analyses were conducted.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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