Ascorbic acid induces osteoblast differentiation of human suspension mononuclear cells

Hadzir SN 1 , Ibrahim SN 1 , Abdul Wahab RM 2 , Zainol Abidin IZ 1 , Senafi S 1 , Ariffin ZZ 3 Show all authors , Abdul Razak M 4 , Zainal Ariffin SH 1

Affiliations 

  • 1 School of Biosciences & Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia
  • 2 Department of Orthodontics, Faculty of Dentistry, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
  • 3 School of Biology, Faculty of Applied Science, Universiti Teknologi MARA, Shah Alam, Selangor, Malaysia. Electronic address: hisham@ukm.my
  • 4 Allianze University College of Medical Sciences, Waziria Medical Square, Kepala Batas, Penang, Malaysia
Cytotherapy, 2014 May;16(5):674-82.
PMID: 24176546 DOI: 10.1016/j.jcyt.2013.07.013

Abstract

Suspension mononuclear cells (MNCs) can be differentiated into osteoblasts with the induction of ascorbic acid and β-glycerophosphate. The aim of this study was to determine the ability of suspension MNCs to differentiate into osteoblasts using ascorbic acid only.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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