Affiliations 

  • 1 School of Chemical Sciences, Universiti Sains Malaysia, Penang 11800 USM, Malaysia
  • 2 Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor Darul Ehsan, Malaysia
Acta Crystallogr E Crystallogr Commun, 2019 Sep 01;75(Pt 9):1379-1382.
PMID: 31523470 DOI: 10.1107/S2056989019011289

Abstract

The title chalcone derivative, C19H20O5, adopts a trans configuration with respect to the olefinic C=C double bond. The 2-hy-droxy-4-methyl-phenyl ring is coplanar with the attached enone bridge [torsion angle = -179.96 (14)°], where this plane is nearly perpendicular to the 2,4,6-tri-meth-oxy-phenyl ring [dihedral angle = 75.81 (8)°]. In the crystal, mol-ecules are linked into chains propagating along [010] by an O-H⋯O hydrogen bond. These chains are further connected into centrosymmetric dimer chains via weak C-H⋯O inter-actions. The conformations of related chalcone derivatives are surveyed and all of these structures adopt a skeleton with two almost orthogonal aromatic rings.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.