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Validation of R-hf risk score for risk stratification in ischemic heart failure patients: A prospective cohort study

Rajan R 1 , Soman SO 2 , Al Jarallah M 1 , Kobalava Z 3 , Dashti R 1 , Al Zakwani I 4 Show all authors , Al Balool J 5 , Tse G 6 , Setiya P 7 , Brady PA 8 , Al-Saber A 9 , Vijayaraghavan G 10

Affiliations 

  • 1 Department of Cardiology, Sabah Al Ahmed Cardiac Centre, Kuwait City, Kuwait
  • 2 Department of Cardiology, Badr Al Samaa Hospital, Ruwi, Muscat, Oman
  • 3 Department of Internal Diseases with Courses of Cardiology and Functional Diagnostics, Peoples' Friendship University of Russia (RUDN University), Moscow, Russia
  • 4 Department of Pharmacology & Clinical Pharmacy, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman
  • 5 Faculty of Medicine, Kuwait University, Jabria, Kuwait
  • 6 Cardiovascular Analytics Group, Hong Kong, China, Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, 300211, China
  • 7 Department of Agrometeorology, College of Agriculture, G.B.Pant University of Agriculture & Technology, Pantnagar, Uttarakhand, India
  • 8 Department of Cardiology, Illinois Masonic Medical Center, Chicago, IL, USA
  • 9 Department of Mathematics and Statistics, University of Strathclyde, Glasgow, G1 1XH, UK
  • 10 Department of Cardiology, Kerala Institute of Medical Sciences, Kerala, India
Ann Med Surg (Lond), 2022 Aug;80:104333.
PMID: 35992211 DOI: 10.1016/j.amsu.2022.104333

Abstract

BACKGROUND: The aim of this study was to validate R-heart failure (R-hf) risk score in ischemic heart failure patients.

METHODS: We prospectively recruited a cohort of 179 ischemic and 107 non-ischemic heart failure patients. This study mainly focused on ischemic heart failure patients. Non-ischemic heart failure patients were included for the purpose of validation of the risk score in various heart failure groups. Patients were stratified in high risk, moderate risk and low risk groups according to R-hf risk score.

RESULTS: A total of 179 participants with ischemic heart failure were included. Based on R-hf risk score, 82 had high risk, 50 had moderate risk and 47 had low risk heart failure scores. More than half of the patients having R-hf score of <5 had renal failure (n = 91, 50.8%) and anemia (n = 99, 55.3%). Notably, HFrEF was more prevalent in patients with high risk score (74, 90.2%). Patients with high risk score had significantly higher creatinine (2.63 ± 1.96, p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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