Affiliations 

  • 1 Neuroscience Research Strength, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Selangor, Malaysia. Electronic address: irmawati.ngadimon@monash.edu
  • 2 Neuroscience Research Strength, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Selangor, Malaysia; School of Dentistry and Medical Sciences, Charles Sturt University, Australia. Electronic address: farooq.shaikh@monash.edu
  • 3 Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Selangor, Malaysia; School of Public Health, The University of Queensland, Brisbane, Australia
  • 4 School of Pharmacy, Monash University Malaysia, Selangor, Malaysia
  • 5 Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; Neurology Unit, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, Malaysia; Centre for Global Epilepsy, Wolfson College, University of Oxford, Oxford, United Kingdom
Drug Discov Today, 2024 Dec;29(12):104247.
PMID: 39571887 DOI: 10.1016/j.drudis.2024.104247

Abstract

Epilepsy, a complex global neurological disorder, has spurred extensive research efforts focused on enhancing diagnostic and therapeutic strategies, with a growing emphasis on the identification of biomarkers. This bibliometric study examines 1,774 publications from 2000 to 2023, revealing a notable increase in research activity, particularly in the past decade. The US, China, and the UK lead contributions, with Asian countries exhibiting growing potential. Keyword co-occurrence analysis reveals a shift towards investigations of neuroinflammatory and genetic biomarkers, as well as emerging areas such as artificial intelligence and epigenetics. Content analysis links specific epilepsy aetiologies to biomarkers, offering promising possibilities for personalised diagnostics and treatments. These findings yield valuable insights into current trends, guiding future research and informing the development of targeted approaches for the diagnosis and treatment of epilepsy.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.