Correlation of the fluorescein dye disappearance test and endoscopic dye transit time in patients after surgery for nasolacrimal duct obstruction

Tai ELM 1 , Amirul-Hasbi TP 2 , Zamli AH 3 , Rajet KA 4 , Kueh YC 5

Affiliations 

  • 1 Department of Ophthalmology and Visual Science, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia; Hospital University Sains Malaysia, Jalan Raja Perempuan Zainab 2, Kota Bharu Kelantan 16150, Malaysia; Department of Ophthalmology, Hospital Tengku Ampuan Afzan, Jalan Tanah Putih, 25100 Kuantan, Pahang, Malaysia. Electronic address: daileid@yahoo.com
  • 2 Department of Ophthalmology and Visual Science, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia; Hospital University Sains Malaysia, Jalan Raja Perempuan Zainab 2, Kota Bharu Kelantan 16150, Malaysia; Department of Ophthalmology, Hospital Tengku Ampuan Afzan, Jalan Tanah Putih, 25100 Kuantan, Pahang, Malaysia
  • 3 Department of Ophthalmology, Hospital Tengku Ampuan Afzan, Jalan Tanah Putih, 25100 Kuantan, Pahang, Malaysia
  • 4 Department of Otorhinolaryngology, Hospital Tengku Ampuan Afzan, Jalan Tanah Putih, 25100 Kuantan, Pahang, Malaysia
  • 5 Biostatistics and Research Methodology Unit, School of Medical Sciences, Health Campus, University Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia
J Fr Ophtalmol, 2024 Dec 19;48(3):104388.
PMID: 39706130 DOI: 10.1016/j.jfo.2024.104388

Abstract

PURPOSE: To correlate fluorescein dye disappearance test (FDDT) grades and endoscopic dye transit times (EDTT) in patients with patent osteotomies after nasolacrimal duct obstruction surgery (NLDO).

DESIGN: Cross-sectional study.

METHODS: All adult patients with patent osteotomies post-external dacryocystorhinostomy (Ex-DCR) or post-endoscopic dacryocystorhinostomy (EDCR) for NLDO were included in this cross-sectional investigation. Patients with dry eye and endoscopically unidentified osteotomy sites were excluded from the study. The FDDT grade, EDTT and lacrimal symptom questionnaire (Lac-Q) scores were documented for all patients.

RESULTS: This study included 39 patients. Nineteen had undergone EDCR, twenty Ex-DCR. The FDDT grade and EDTT were positively correlated (r=0.32, P=0.045). The mean Lac-Q score was not correlated with FDDT grade (r=-0.01, P=0.951) or EDTT (r=0.07, P=0.669). There were no significant differences in the FDDT grade, EDTT, Lac-Q score or ostial characteristics between Ex-DCR and EDCR.

CONCLUSION: FDDT grading correlates with EDTT, suggesting that these tests may be used interchangeably based on the clinician's ease of access and instrumentation. There was no correlation between the symptoms of lacrimal outflow obstruction with objective evidence of drainage.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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