Headache Secondary to Sphenoid Sinus Fungal Mycetoma

Sphenoid sinus fungal ball is a rare occurrence. To diagnose isolated sphenoid sinus fungal ball pathology accurately and promptly, a high index of clinical suspicion, routine office nasal endoscopy, and radiological imaging are essential. In this case report, we discuss a woman in her 60s who presented with chronic generalized headache. Incidental findings of computed tomography of the brain revealed a lesion in the sphenoid sinus, which was later diagnosed and treated as a fungal mycetoma.