Silicon carbide and zirconium nitride-based surface plasmon resonance sensors for detecting Serratia marcescens and Micrococcus lysodeikticus

Hsu CY 1 , Kanjariya P 2 , Ariffin IA 3 , Rajiv A 4 , Kashyap A 5 , Jebaselvi GDA 6 Show all authors , Choudhury S 7 , Yadav Y 8 , Rao PS 9 , Shah SK 10 , Pal A 11

Affiliations 

  • 1 Thunderbird School of Global Management, Arizona State University, Tempe Campus, Phoenix, AZ, 85004, USA
  • 2 Marwadi University Research Center, Department of Physics, Faculty of Science, Marwadi University, Rajkot, Gujarat, India
  • 3 Management and Science University, Shah Alam, Selangor, Malaysia
  • 4 Department of Physics & Electronics, School of Sciences, JAIN (Deemed to Be University), Bangalore, Karnataka, India
  • 5 Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab, 140401, India
  • 6 Department of Electronics and Communication Engineering, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India
  • 7 Department of Electrical & Electronics Engineering, Siksha O Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751030, India
  • 8 Department of Electrical, NIMS Institute of Engineering & Technology, NIMS University Rajasthan Electronics & Electric Vehicle Engineering, Jaipur, India
  • 9 Department of ECE, Raghu Engineering College, Visakhapatnam, Andhra Pradesh , 531162, India
  • 10 Department of Electronics & Communication Engineering, Uttaranchal Institute of Technology, Uttaranchal University, Dehradun, Uttarakhand, 248007, India
  • 11 Department of ECE, University Centre for Research and Development, Chandigarh University, Gharuan, Mohali, 140413, India. amrindra.ieee@gmail.com
Mikrochim Acta, 2025 Apr 16;192(5):302.
PMID: 40240726 DOI: 10.1007/s00604-025-07161-6

Abstract

A novel surface plasmon resonance (SPR) biosensor design for point-of-care detection of different bacteria is presented. It consists of a SiO2 prism, metal (Ag), silicon carbide (SiC), 2D materials of zirconium nitride (ZrN), and a sensing medium. The proposed structure's angular reflectivity is investigated using the transfer matrix method (TMM) following optimization of the Ag and SiC layer thicknesses. For the various types of bacteria such as Staphylococcus (S) aureus, faecalis 9790, aureus Duncan, and aureus 52A5, the maximal sensitivity of 327, 362.45, 301.46, and 269.87°/RIU is achieved with remarkable minimum reflectance (Rmin). According to simulation results, using a new class of 2D materials significantly improves the sensor performance over the conventional SPR configuration. Furthermore, the proposed SPR structure is presented with COMSOL Multiphysics to measure the electric field enhancement factor and intensity close to the ZrN material-sensing layer interface. Using the fabrication technologies to fabricate the proposed sensor as an SPR chip is worthwhile due to its real-time and label-free detection of malaria diseases.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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