Affiliations 

  • 1 Professor, Department of Conservative Dentistry & Endodontics, Faculty of Dental Sciences, Sri Ramachandra University , Porur, Chennai, India
  • 2 Senior Lecturer, Department of Restorative Dentistry, International Medical University , Kula Lumpur, Malaysia
  • 3 Former Post Graduate, Department of Conservative Dentistry & Endodontics, Faculty of Dental Sciences, Sri Ramachandra University , Porur, Chennai, India
  • 4 Dean, Professor and Head, Department of Conservative Dentistry & Endodontics, Faculty of Dental Sciences, Sri Ramachandra University , Porur, Chennai, India
J Clin Diagn Res, 2015 Nov;9(11):ZC61-5.
PMID: 26675655 DOI: 10.7860/JCDR/2015/14602.6829

Abstract

Enterococcus faecalis is one of the most commonly occurring organisms retrieved from root canal treated teeth that show refractory apical periodontitis. Though it is well known that the ability of E. faecalis to form a matrix-encased biofilm contributes to its pathogenicity, the role of extracellular dextran and DNA in biofilm formation and its effect on the susceptibility of the biofilm to chlorhexidine remains poorly understood. It was hypothesized that the addition of an Extracellular Polymeric Substance (EPS) degrading enzyme along with a detergent to chlorhexidine may increase the susceptibility of the E. faecalis biofilm.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.