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Neurite outgrowth stimulatory effects of myco synthesized AuNPs from Hericium erinaceus (Bull.: Fr.) Pers. on pheochromocytoma (PC-12) cells

Raman J 1 , Lakshmanan H 1 , John PA 2 , Zhijian C 3 , Periasamy V 3 , David P 4 Show all authors , Naidu M 4 , Sabaratnam V 2

Affiliations 

  • 1 Mushroom Research Centre, University of Malaya, Kuala Lumpur, Malaysia
  • 2 Mushroom Research Centre, University of Malaya, Kuala Lumpur, Malaysia ; Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
  • 3 Low Dimensional Materials Research Center (LDMRC), Department of Physics, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
  • 4 Mushroom Research Centre, University of Malaya, Kuala Lumpur, Malaysia ; Department of Anatomy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Int J Nanomedicine, 2015;10:5853-63.
PMID: 26425086 DOI: 10.2147/IJN.S88371

Abstract

Hericium erinaceus has been reported to have a wide range of medicinal properties such as stimulation of neurite outgrowth, promotion of functional recovery of axonotmetic peroneal nerve injury, antioxidant, antihypertensive, and antidiabetic properties. In recent years, the green synthesis of gold nanoparticles (AuNPs) has attracted intense interest due to the potential use in biomedical applications. The aim of this study was to investigate the effects of AuNPs from aqueous extract of H. erinaceus on neurite outgrowth of rat pheochromocytoma (PC-12) cells.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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