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Increased serum levels of interleukin-6 and von Willenbrand Factor in early phase of acute coronary syndrome in a young and multiethnic Malaysian population

Tiong WN 1 , Fong AY 2 , Sim EU 3 , Chan HC 4 , Ong TK 5 , Chang BC 5 Show all authors , Sim KH 5

Affiliations 

  • 1 Clinical Research Centre, Sarawak General Hospital, Jalan Tun Ahmad Zaidi Adruce, Kuching, Sarawak, Malaysia; Department of Molecular Biology, University Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia
  • 2 Clinical Research Centre, Sarawak General Hospital, Jalan Tun Ahmad Zaidi Adruce, Kuching, Sarawak, Malaysia; Department of Cardiology, Sarawak General Hospital, Jalan Tun Ahmad Zaidi Adruce, Kuching, Sarawak, Malaysia
  • 3 Department of Molecular Biology, University Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia
  • 4 Accident and Emergency Department, Sarawak General Hospital, Jalan Tun Ahmad Zaidi Adruce, Kuching, Sarawak, Malaysia
  • 5 Department of Cardiology, Sarawak General Hospital, Jalan Tun Ahmad Zaidi Adruce, Kuching, Sarawak, Malaysia
Heart Asia, 2012;4(1):146-50.
PMID: 27326052 DOI: 10.1136/heartasia-2012-010131

Abstract

Interleukin-6 (IL6; proinflammatory marker), von Willebrand Factor (vWF; endothelial dysfunction marker) and P-selectin (platelet activation marker), may play important roles in defining the pathogenesis of vulnerable plaques in acute coronary syndrome (ACS). This study aims to investigate the expression and relationship of these markers in early phases of ACS in a young and multiethnic Malaysian population.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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