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Detection of Salivary IgA Antibodies Against the HlyE Antigen as a Diagnosis of Typhoid Fever

Chin KL 1 , Redhuan NE 2 , Balaram P 3 , Phua KK 4 , Ong EB 5

Affiliations 

  • 1 PhD Student, Institute for Research in Molecular Medicine, Universiti Sains , Malaysia, 11800 Pulau Pinang, Malaysia
  • 2 PhD Student, School of Veterinary Medicine, Universiti Malaysia Kelantan , Kota Bharu, Kelantan, Malaysia
  • 3 Former Professor, Institute for Research in Molecular Medicine, Universiti Sains , Malaysia, 11800 Pulau Pinang, Malaysia
  • 4 Professor, Institute for Research in Molecular Medicine, Universiti Sains , Malaysia, 11800 Pulau Pinang, Malaysia
  • 5 Lecturer, Institute for Research in Molecular Medicine, Universiti Sains , Malaysia, 11800 Pulau Pinang, Malaysia
J Clin Diagn Res, 2016 Jun;10(6):DM01-3.
PMID: 27504289 DOI: 10.7860/JCDR/2016/17801.7909

Abstract

The Salmonella typhi (S. typhi) haemolysin E protein (HlyE) has been shown to be a sensitive and specific antigen for the detection of typhoid fever through the detection of anti-HlyE antibodies in sera. Saliva can also be a useful diagnostic fluid as it also contains antibodies against bacterial pathogens.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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