Sulthiame-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome

Fong CY 1 , Hashim N 2 , Gan CS 3 , Chow TK 4 , Tay CG 2

Affiliations 

  • 1 Division of Paediatric Neurology, Department of Paediatrics, University of Malaya, Kuala Lumpur, Malaysia. Electronic address: cyfong@ummc.edu.my
  • 2 Division of Paediatric Neurology, Department of Paediatrics, University of Malaya, Kuala Lumpur, Malaysia
  • 3 Division of Paediatric Intensive Care, Department of Paediatrics, University of Malaya, Kuala Lumpur, Malaysia
  • 4 Department of Pathology, University of Malaya, Kuala Lumpur, Malaysia
Eur. J. Paediatr. Neurol., 2016 Nov;20(6):957-961.
PMID: 27524391 DOI: 10.1016/j.ejpn.2016.07.023

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and potentially life-threatening acute drug-induced hypersensitivity reaction. Antiepileptic drugs (AEDs) predominantly aromatic AEDs are commonly reported in DRESS. To date there are no reports of sulthiame AED causing DRESS syndrome.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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