Fulltext

Genotypic Detection of rpoB and katG Gene Mutations Associated with Rifampicin and Isoniazid Resistance in Mycobacterium Tuberculosis Isolates: A Local Scenario (Kelantan)

Ismail NA 1 , Ismail MF 2 , Noor SS 2 , Camalxaman SN 1

Affiliations 

  • 1 Department of Medical Laboratory Technology, Faculty of Health Sciences, Universiti Teknologi MARA, 42300, Bandar Puncak Alam, Selangor, Malaysia
  • 2 Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
Malays J Med Sci, 2016 Jan;23(1):22-6.
PMID: 27540322 MyJurnal

Abstract

Drug resistant tuberculosis (DR-TB) remains a public health issue that is of major concern on a global scale. The characterisation of clinical isolates may provide key information regarding the underlying mechanisms of drug resistance, and helps to augment therapeutic options. This study aims to evaluate the frequency of gene mutations associated with Rifampicin (RIF) and Isoniazid (INH) resistance among nine clinical isolates.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

MeSH terms
Similar publications