Identification of biomarkers for periodontal disease using the immunoproteomics approach

Kerishnan JP 1 , Mohammad S 2 , Alias MS 2 , Mu AK 3 , Vaithilingam RD 4 , Baharuddin NA 4 Show all authors , Safii SH 4 , Abdul Rahman ZA 5 , Chen YN 6 , Chen Y 7

Affiliations 

  • 1 Department of Oral Science & Craniofacial, Faculty of Dentistry, University of Malaya , Kuala Lumpur , Malaysia
  • 2 Faculty of Dentistry, University of Malaya , Kuala Lumpur , Malaysia
  • 3 Laboratory of Biotechnology, Institute of Win Men Biotech , Sungai Bakap, Pulau Pinang , Malaysia
  • 4 Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya , Kuala Lumpur , Malaysia
  • 5 Department of Oro-Maxillofacial Surgical & Medical Sciences, Faculty of Dentistry, University of Malaya , Kuala Lumpur , Malaysia
  • 6 Chen Dental Specialist Clinic , Kuching, Sarawak , Malaysia
  • 7 Department of Oral Science & Craniofacial, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia; Oral Cancer Research and Coordinating Centre, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia
PeerJ, 2016;4:e2327.
PMID: 27635317 DOI: 10.7717/peerj.2327

Abstract

Periodontitis is one of the most common oral diseases associated with the host's immune response against periodontopathogenic infection. Failure to accurately diagnose the stage of periodontitis has limited the ability to predict disease status. Therefore, we aimed to look for reliable diagnostic markers for detection or differentiation of early stage periodontitis using the immunoprotemic approach.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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