Effect of palm oil (Elaeis guineensis) tocotrienols on mesenteric adipose tissue deposition and the expression of 11β-hydroxysteroid dehydrogenase type 1 enzyme (11β-HSD1) in adrenalectomized rats treated with dexamethasone

Azwan K 1 , Farihah HS 2 , Fairus A 2 , Elvy MR 2

Affiliations 

  • 1 Anatomy Department, Universiti Kuala Lumpur - Royal College of Medicine Perak, 3 Jalan Greentown, Ipoh, Perak, Malaysia
  • 2 Anatomy Department, Faculty of Health Sciences, Universiti Kebangsaan Malaysia Jalan Raja Muda Abdul Aziz 50300 Kuala Lumpur, Malaysia
Clin Ter, 2015;166(3):99-104.
PMID: 26152615 DOI: 10.7417/CT.2015.1837

Abstract

A study was done to investigate the effect of palm oil (Elaeis guineensis) tocotrienols on (1) rats mesenteric adipose tissue deposition (2) and 11β-HSD1 enzyme expression in mesenteric adipocyte. There is a necessity to find an inhibitor for the 11β-HSD1 enzyme which enhances the proliferation of mesenteric adipocyte tissue therefore curbing the onset of metabolic syndrome.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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