• 1 Department of Biological Sciences, Faculty of Science and Technology, Sunway University , Selangor, 47500, Malaysia
ACS Chem Neurosci, 2017 04 19;8(4):687-688.
PMID: 28225265 DOI: 10.1021/acschemneuro.7b00049


Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous. Here, we discuss targeted therapeutic approach to affect parasite viability without affecting the host cells, with an eye to improve formulation of drugs and/or administration of drugs against brain-eating amoebae.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.