Fulltext

Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression

Teah YF 1 , Abduraman MA 2 , Amanah A 1 , Adenan MI 3 , Fariza Sulaiman S 4 , Tan ML 1

Affiliations 

  • 1 Malaysian Institute of Pharmaceuticals & Nutraceuticals, National Institutes of Biotechnology Malaysia (NIBM), Ministry of Science, Technology and Innovation Malaysia, Pulau Pinang, Malaysia
  • 2 Advanced Medical & Dental Institute, Universiti Sains Malaysia, Pulau Pinang, Malaysia
  • 3 Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA (UiTM), Selangor Darul Ehsan, Malaysia
  • 4 School of Biological Sciences, Universiti Sains Malaysia, Pulau Pinang, Malaysia
Data Brief, 2017 Oct;14:584-591.
PMID: 28879216 DOI: 10.1016/j.dib.2017.08.008

Abstract

The data presented in this article are related to the research article entitled "The effects of deoxyelephantopin on the cardiac delayed rectifier potassium channel current (IKr) and human ether-a-go-go-related gene (hERG) expression" (Y.F. Teah, M.A. Abduraman, A. Amanah, M.I. Adenan, S.F. Sulaiman, M.L. Tan) [1], which the possible hERG blocking properties of deoxyelephantopin were investigated. This article describes the construction of human embryonic kidney 293 (HEK293) cells overexpressing HERG potassium channel and verification of the presence of hERG mRNA and protein expression in this recombinant cell line.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

MeSH terms
Similar publications