Trimethoprim-Sulfamethoxazole (TMP-SMX)
or Co-Trimazole is the treatment of choice for
meliodosis. A 52-year-old man presented with
generalized body weakness with reduced appetite.
He had bradycardia on examination. After
investigations, he was diagnosed as hyperkalaemia.
He had life-threatening hyperkalaemia treated
with Trimethoprim-Sulfamethoxazole (TMPSMX)
as part of the eradication therapy for
Meliodosis. Urgent haemodialysis was done. There
were changes done for his meliodosis treatment.
This case wished to highlight the importance of
considering hyperkalemia in patient treated with
Trimethoprim-Sulfamethoxazole especially when
risk factor for hyperkalaemia is present.